ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q8UBM8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name PUR9_AGRT5
Primary accession number Q8UBM8
Secondary accession numbers None
Integrated into Swiss-Prot on June 20, 2003
Sequence was last modified on June 20, 2003 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 37)
Name and origin of the protein
Protein name Bifunctional purine biosynthesis protein purH
Synonyms None
Includes Phosphoribosylaminoimidazolecarboxamide formyltransferase
     (EC 2.1.2.3)
     (AICAR transformylase)
IMP cyclohydrolase
     (EC 3.5.4.10)
     (Inosinicase)
     (IMP synthetase)
     (ATIC)
Gene name
Name: purH
OrderedLocusNames: Atu2823
ORFNames: AGR_C_5117
From
Agrobacterium tumefaciens (strain C58 / ATCC 33970) [TaxID: 176299] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066804; PubMed=11743193 [NCBI, ExPASy, EBI, Israel, Japan]
Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W.;
"The genome of the natural genetic engineer Agrobacterium tumefaciens C58.";
Science 294:2317-2323(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066803; PubMed=11743194 [NCBI, ExPASy, EBI, Israel, Japan]
Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.";
Science 294:2323-2328(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE007869; AAK88535.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AF2923; AF2923.
F97697; F97697.
RefSeq NP_355750.2; -.
3D structure databases
HSSP P31335; 1G8M. [HSSP ENTRY / PDB]
ModBase Q8UBM8.
Ontologies
GO
GO:0003937; Molecular function: IMP cyclohydrolase activity (inferred from electronic annotation from HAMAP).
GO:0004643; Molecular function: phosphoribosylaminoimidazolecarboxamide formyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006188; Biological process: IMP biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00139; -; 1.
PBIL [Tree]
InterPro IPR002695; AICARFT_IMPCHas.
IPR013982; AICARFT_IMPCHas_formly.
IPR011607; MGS.
Graphical view of domain structure.
PANTHER PTHR11692; AICARFT_IMPCHas; 1.
Pfam PF01808; AICARFT_IMPCHas; 1.
PF02142; MGS; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000414; AICARFT_IMPCHas; 1.
SMART SM00798; AICARFT_IMPCHas; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00355; purH; 1.
ProtoNet Q8UBM8.
Genome annotation databases
GeneID 1134861; -.
GenomeReviews AE007869_GR; Atu2823.
KEGG atc:AGR_C_5117; -.
atu:Atu2823; -.
Phylogenomic databases
HOGENOM Q8UBM8; -.
Genome annotation databases
CMR Q8UBM8; Atu2823.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Multifunctional enzyme; Purine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   538  538     Bifunctional purine biosynthesis protein purH. PRO_0000192066
Sequence information
Length: 538 AA [This is the length of the unprocessed precursor] Molecular weight: 56891 Da [This is the MW of the unprocessed precursor] CRC64: A08254F00C5764BC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAVVSKKIPA PDKVKIRTAL LSVSDKTDII ELATVLSKLG VKLLSTGGTA KAIAEAGLAV 

        70         80         90        100        110        120 
TDVSDVTNFP EIMDGRVKTL HPNVHGGLLA IRDDAEHVEA MKAHGIEAID LSVINLYPFE 

       130        140        150        160        170        180 
EVRAKGGDYP TTVENIDIGG PAMIRASAKN HAYVTVVTDP SDYPALVEAL QADDGQTSYA 

       190        200        210        220        230        240 
LRQRFAAKAY ARTAAYDAVI SNWFAEALAI ETPHYRAIGG VLKEKMRYGE NPHQSAGFYL 

       250        260        270        280        290        300 
TGEKRPGVAT ATLLQGKQLS YNNINDTDAA YELVAEFLPE NAPAVAIVKH ANPCGVATGP 

       310        320        330        340        350        360 
TLAEAYRRAL ACDSVSAFGG VIALNRTLDA ETAEEIVKLF TEVIIAPDVT EEAKSIIARK 

       370        380        390        400        410        420 
PNLRLLAAGG LPDPRAAGLT AKTVSGGLLV QSRDNGMVED LELKVVTKRA PTAQELEDMK 

       430        440        450        460        470        480 
FAFKIAKHVK SNAVIYAKDG QTAGIGAGQM SRVDSARIAA QKAEDAAKAL GLAEPLTRGS 

       490        500        510        520        530 
AVASEAFYPF ADGLLAAIAA GATAVIQPGG SMRDQDVIDA ANEHNVAMVF TGMRHFRH 

Q8UBM8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ch flag SIB Switzerland Mirror sites: Australia  Brazil  Canada  China  Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!