ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q8UAS9


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name THIM_AGRT5
Primary accession number Q8UAS9
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 2002
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 48)
Name and origin of the protein
Protein name Probable hydroxyethylthiazole kinase
Synonyms EC 2.7.1.50
4-methyl-5-beta-hydroxyethylthiazole kinase
Thz kinase
TH kinase
Gene name
Name: thiM
OrderedLocusNames: Atu3288
ORFNames: AGR_L_3060
From
Agrobacterium tumefaciens (strain C58 / ATCC 33970) [TaxID: 176299] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066804; PubMed=11743193 [NCBI, ExPASy, EBI, Israel, Japan]
Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P., Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V., Nester E.W.;
"The genome of the natural genetic engineer Agrobacterium tumefaciens C58.";
Science 294:2317-2323(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1066803; PubMed=11743194 [NCBI, ExPASy, EBI, Israel, Japan]
Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M., Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
"Genome sequence of the plant pathogen and biotechnology agent Agrobacterium tumefaciens C58.";
Science 294:2323-2328(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE007870; AAK90102.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR AB2961; AB2961.
D98322; D98322.
RefSeq NP_357317.1; -.
3D structure databases
HSSP P39593; 1EKQ. [HSSP ENTRY / PDB]
ModBase Q8UAS9.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004417; Molecular function: hydroxyethylthiazole kinase activity (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0009228; Biological process: thiamin biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00228; atypical; 1.
PBIL [Tree]
InterPro IPR000417; Hyethyz_kinase.
IPR011144; Hyethyz_kinsmonf.
Graphical view of domain structure.
PANTHER PTHR20857:SF14; Hyethyz_kinase; 1.
Pfam PF02110; HK; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000513; Thz_kinase; 1.
PRINTS PR01099; HYETHTZKNASE.
ProtoNet Q8UAS9.
Genome annotation databases
GeneID 1135162; -.
GenomeReviews AE007870_GR; Atu3288.
KEGG atc:AGR_L_3060; -.
atu:Atu3288; -.
Phylogenomic databases
HOGENOM Q8UAS9; -.
Genome annotation databases
CMR Q8UAS9; Atu3288.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Thiamine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   246  246     Probable hydroxyethylthiazole kinase. PRO_0000156923
METAL   99    99        Magnesium 1 (By similarity). 
METAL   130   130        Magnesium 1 (By similarity). 
BINDING   50    50        Substrate; via amide nitrogen (By similarity). 
BINDING   125   125        ATP (By similarity). 
BINDING   145   145        ATP (By similarity). 
BINDING   172   172        Substrate; via amide nitrogen (By similarity). 
Sequence information
Length: 246 AA [This is the length of the unprocessed precursor] Molecular weight: 26345 Da [This is the MW of the unprocessed precursor] CRC64: 27E5AC411493BCAF [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSGDFPTAAR AAEILERVRQ MRPRVHCLMN TVVQKFTADG ITVIGGIPSM TTSLEEIESF 

        70         80         90        100        110        120 
VTKADALTVN LGTLDAERRR VIRLAIEIAN ASGKPWIVDP VHVDYSPSRL DFARELIAQS 

       130        140        150        160        170        180 
PTIVRGNRAE MSLIGDVPDV VRIETGPVDH LRDRTRNVSI VNGHPWMAKV TGTGCLSGGV 

       190        200        210        220        230        240 
IAAFMAVEKD ALTAAASALA VTGVSAELAA QRAKGPGTFE PAFLDALSEI SGEDIINHAR 


IEHEQG 

Q8UAS9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ch flag SIB Switzerland Mirror sites: Australia  Brazil  Canada  China  Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!