[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1; Weiss R.B., Dunn D.M., Robb F.T., Brown J.R.; "The complete sequence of the Pyrococcus furiosus genome."; Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG) (By similarity).
CATALYTIC ACTIVITY: 2(alpha-D-mannosyl)-3-phosphoglycerate + H₂O = 2(alpha-D-mannosyl)-D-glycerate + phosphate.
PATHWAY: Carbohydrate biosynthesis; mannosylglycerate biosynthesis; 2(alpha-D-mannosyl)-D-glycerate from GDP-D-mannose (MPG route): step 2/2 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the HAD-like hydrolase superfamily. MPGP family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AE010181; AAL80714.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_578319.2; -.

3D structure databases

ModBase

Q8U381.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0050531;	Molecular function: mannosyl-3-phosphoglycerate phosphatase activity (inferred from electronic annotation from InterPro).
GO:0051479;	Biological process: mannosylglycerate biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

HAMAP

MF_00617; -; 1.
PBIL [Tree]

InterPro

IPR013200; HAD-SF_hydro-like_3.
IPR006379; HAD-SF_hydro_IIB.
IPR006381; HAD-SF_hydro_IIB_YedP.
IPR012813; Osmo_MPG_phos.
Graphical view of domain structure.

Pfam

PF08282; Hydrolase_3; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR01484; HAD-SF-IIB; 1.
TIGR01486; HAD-SF-IIB-MPGP; 1.
TIGR02461; osmo_MPG_phos; 1.

ProtoNet

Q8U381.

Genome annotation databases

1468433; -.

AE009950_GR; PF0590.

pfu:PF0590; -.

fig|186497.1.peg.604; -.

Phylogenomic databases

HOGENOM

Q8U381; -.

Other

LinkHub

Q8U381; -.

Genome annotation databases

CMR

Q8U381; PF0590.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Hydrolase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 242`	`242`		`Mannosyl-3-phosphoglycerate phosphatase.`	`PRO_0000184972`

Sequence information

Length: 242 AA [This is the length of the unprocessed precursor]

Molecular weight: 28022 Da [This is the MW of the unprocessed precursor]

CRC64: 133DE5E84FB0AC02 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MIRVIFLDLD KTLLPEYDPE PAIPIVEELK KKGFEIVFNS SKTRAEQEYY REKLNVKGPF 

        70         80         90        100        110        120 
IVENGSAIYI PSNYFPFEVP GVKRGEYMVL ELGVKVEEIR KALKELEAEY GLKYYGNSTD 

       130        140        150        160        170        180 
EEIEKFTKLP KHLIPLAKDR EYSETIFLWK REGWEKDLIR KGFKVTMGSR FYAVHGNSDK 

       190        200        210        220        230        240 
GKAAKLLLDL YKRVDEVESY AVGDGENDFP MFDVVDFAFL IGDLRHENAE NVTSIKDVLK 


KI

Q8U381 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools