[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1; Weiss R.B., Dunn D.M., Robb F.T., Brown J.R.; "The complete sequence of the Pyrococcus furiosus genome."; Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Catalyzes the dephosphorylation of 2-phosphoglycolate (By similarity).
CATALYTIC ACTIVITY: 2-phosphoglycolate + H₂O = glycolate + phosphate.
COFACTOR: Magnesium (By similarity).
SIMILARITY: Belongs to the archaeal SPP-like hydrolase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AE010245; AAL81543.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_579148.1; -.

3D structure databases

SMR

Q8U111; 1-231.

ModBase

Q8U111.

Ontologies

GO:0000287;	Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0008967;	Molecular function: phosphoglycolate phosphatase activity (inferred from electronic annotation from HAMAP).
GO:0005975;	Biological process: carbohydrate metabolic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

HAMAP

MF_01419; -; 1.
PBIL [Tree]

InterPro

IPR005834; Dehalogen-like_hydro.
IPR006379; HAD-SF_hydro_IIB.
IPR006382; SPPlik_hydro_arc.
IPR006378; Suc_phosP.
Graphical view of domain structure.

Pfam

PF00702; Hydrolase; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR01484; HAD-SF-IIB; 1.
TIGR01487; SPP-like; 1.
TIGR01482; SPP-subfamily; 1.

ProtoNet

Q8U111.

Genome annotation databases

1469295; -.

AE009950_GR; PF1419.

pfu:PF1419; -.

fig|186497.1.peg.1466; -.

Phylogenomic databases

HOGENOM

Q8U111; -.

Genome annotation databases

CMR

Q8U111; PF1419.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Carbohydrate metabolism; Complete proteome; Hydrolase; Magnesium; Metal-binding.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 231`	`231`	`Phosphoglycolate phosphatase.`	`PRO_0000146724`
`ACT_SITE`	`9 9`		`Nucleophile (By similarity).`
`METAL`	`9 9`		`Magnesium (By similarity).`
`METAL`	`11 11`		`Magnesium (By similarity).`
`METAL`	`177 177`		`Magnesium (By similarity).`
`METAL`	`181 181`		`Magnesium (By similarity).`
`BINDING`	`154 154`		`Substrate (By similarity).`

Sequence information

Length: 231 AA [This is the length of the unprocessed precursor]

Molecular weight: 25506 Da [This is the MW of the unprocessed precursor]

CRC64: CA251F366C743441 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKIKAISLDI DGTITYPNRM IHEEALQAIR KAESLGVPIM LVTGNTVQFA EAASILIGTS 

        70         80         90        100        110        120 
GPVVAEDGGA ISYKKKRIFL TSMDEEWILW GELKKRFPNV KTSHTMPDRR AGLVIMRETI 

       130        140        150        160        170        180 
DVETVRKLIK ELNLNLVAVD SGFAIHVKKP WINKGSGIEK ACELLGLNPK EVAHVGDGEN 

       190        200        210        220        230 
DLDAFKVVGY RIAVAQAPKI LKENADYITQ NEYGKGGAEA IYHILEKFGY I

Q8U111 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools