[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1; Weiss R.B., Dunn D.M., Robb F.T., Brown J.R.; "The complete sequence of the Pyrococcus furiosus genome."; Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: L-arginine = agmatine + CO₂.
COFACTOR: Pyruvoyl group (By similarity).
SIMILARITY: Belongs to the pdaD family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AE010262; AAL81747.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_579352.1; -.

3D structure databases

HSSP

Q57764; 1N2M. [HSSP ENTRY / PDB]

ModBase

Q8U0G6.

Ontologies

GO:0008792;	Molecular function: arginine decarboxylase activity (inferred from electronic annotation from HAMAP).
GO:0006527;	Biological process: arginine catabolic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

HAMAP

MF_01404; -; 1.
PBIL [Tree]

InterPro

IPR016105; Pyr-dep_his/arg-deCO2ase_sand.
IPR002724; Pyruvoyl-dep_arg_deCO2ase.
Graphical view of domain structure.

Gene3D

G3DSA:3.50.20.10; Pyr-dep_his/arg-deCO2ase_sand; 1.

Pfam

PF01862; PvlArgDC; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF005216; Pyruvoyl-dep_arg_deCO2ase; 1.

ProDom

PD010449; DUF44; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGRFAMs

TIGR00286; PvlArgDC; 1.

ProtoNet

Q8U0G6.

Genome annotation databases

1469500; -.

AE009950_GR; PF1623.

pfu:PF1623; -.

fig|186497.1.peg.1671; -.

Phylogenomic databases

HOGENOM

Q8U0G6; -.

Genome annotation databases

CMR

Q8U0G6; PF1623.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Decarboxylase; Lyase; Pyruvate.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 43`	`43`	`Pyruvoyl-dependent arginine decarboxylase subunit beta (By similarity).`	`PRO_0000023330`
`CHAIN`	`44 158`	`115`	`Pyruvoyl-dependent arginine decarboxylase subunit alpha (By similarity).`	`PRO_0000023331`
`SITE`	`43 44`	`2`	`Cleavage (non-hydrolytic) (By similarity).`
`MOD_RES`	`44 44`		`Pyruvic acid (Ser) (By similarity).`

Sequence information

Length: 158 AA [This is the length of the unprocessed precursor]

Molecular weight: 17108 Da [This is the MW of the unprocessed precursor]

CRC64: 6441F3D6306F200C [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSWITPKKAI MLAAAAEGGT KLNAFDNALL KMGIGNVNLV KLSSVIPAHI EWLDELPKNI 

        70         80         90        100        110        120 
PIGMLLPTVY THIESDEPGS TISAALGIGL SEGNEGGLIY EYSGYCKKEE AEEMVKKMVE 

       130        140        150 
EGFRVRGWKL KEIKIVSAEI TVKDKPAAAV AAVVMFPY

Q8U0G6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools