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UniProtKB/Swiss-Prot entry Q8TNH5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ADEC_METAC
Primary accession number Q8TNH5
Secondary accession numbers None
Integrated into Swiss-Prot on August 16, 2004
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 32)
Name and origin of the protein
Protein name Adenine deaminase
Synonyms Adenase
Adenine aminase
EC 3.5.4.2
Gene name
Name: ade
Synonyms: adeC
OrderedLocusNames: MA_2310
From
Methanosarcina acetivorans [TaxID: 2214] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanomicrobia; Methanosarcinales; Methanosarcinaceae; Methanosarcina.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
DOI=10.1101/gr.223902; PubMed=11932238 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W., Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J., Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P., McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D., Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R., Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J., Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A., White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H., Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V., Zinder S.H., Lander E., Metcalf W.W., Birren B.;
"The genome of Methanosarcina acetivorans reveals extensive metabolic and physiological diversity.";
Genome Res. 12:532-542(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE010299; AAM05703.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_617223.1; -.
3D structure databases
ModBase Q8TNH5.
Enzyme and pathway databases
BioCyc MACE188937:MA2310-MON; -.
Ontologies
GO
GO:0000034; Molecular function: adenine deaminase activity (inferred from electronic annotation from HAMAP).
GO:0030145; Molecular function: manganese ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006146; Biological process: adenine catabolic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_01518; -; 1.
PBIL [Tree]
InterPro IPR006679; Adenine_deam.
IPR006680; Amidohydro_1.
Graphical view of domain structure.
Pfam PF01979; Amidohydro_1; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01178; ade; 1.
ProtoNet Q8TNH5.
Genome annotation databases
GeneID 1474199; -.
GenomeReviews AE010299_GR; MA_2310.
KEGG mac:MA2310; -.
NMPDR fig|188937.1.peg.2249; -.
Phylogenomic databases
HOGENOM Q8TNH5; -.
Genome annotation databases
CMR Q8TNH5; MA_2310.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Manganese.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   553  553     Adenine deaminase. PRO_0000142439
Sequence information
Length: 553 AA [This is the length of the unprocessed precursor] Molecular weight: 60731 Da [This is the MW of the unprocessed precursor] CRC64: C58B219A5AEF73DB [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKKYLGIIVD AVSRRQFKGE ITVENGKILR VEEKEHDHER YILPGLVDAH VHIESSMTVP 

        70         80         90        100        110        120 
SVFARMAVAK GTVAVVSDPH EIANVMGEEG IDFMLGDSKR SPLKVFFGVP SCVPATPFES 

       130        140        150        160        170        180 
AGSVLDAEAV DRLLAREDLY YLSEMMNFPG VVLGFPDVMA KLESAKKCGK VIDGHAPGLR 

       190        200        210        220        230        240 
GADLETYIGV GISTDHESFT YEEAVEKIKL GMKILIREGS SARNFETLYS LIDEYPEAVM 

       250        260        270        280        290        300 
LCTDDSHPDT LIYEGHIDKL IRRGQEKGLD IFNLIRAAVI NPVEHYGLNV GLLREGDPAD 

       310        320        330        340        350        360 
FITVDDLKSF NVLSTFIDGE CVYENGKVLF PMKKVPAKNV FNRNKISIDA AKLAVPAEET 

       370        380        390        400        410        420 
GDRKEGMRKI RVIVARDGEL VTGQELAFPK VENGNMVSDP EKDILKMVVL SRYADDPVQI 

       430        440        450        460        470        480 
GFIKNIGLKE GAIASSIAHD SHNIIAVGAT DKDIVEAVNR LVENKGGIVV GTAENLLDLP 

       490        500        510        520        530        540 
LEVAGLMSTL DGVEVASRYR LLNEEARKLG TSLESPFMTL AFMSLLVIPE LKLGDKGLFD 

       550 
VTKFEFVELF AEE 

Q8TNH5 in FASTA format

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