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UniProtKB/Swiss-Prot entry Q8TGG8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GDA1_ASPFU
Primary accession number Q8TGG8
Secondary accession numbers Q4WSN7 Q6MYR7
Integrated into Swiss-Prot on April 13, 2004
Sequence was last modified on December 6, 2005 (Sequence version 2)
Annotations were last modified on    November 4, 2008 (Entry version 37)
Name and origin of the protein
Protein name Probable guanosine-diphosphatase
Synonyms GDPase
EC 3.6.1.42
Gene name
Name: gda1
ORFNames: AfA14E5.03c, AFUA_1G12150
From
Aspergillus fumigatus (Sartorya fumigata) [TaxID: 5085] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Af293 / CBS 101355 / FGSC A1100;
DOI=10.1016/j.fgb.2003.12.003; PubMed=14998527 [NCBI, ExPASy, EBI, Israel, Japan]
Pain A., Woodward J.R., Quail M.A., Anderson M.J., Clark R., Collins M., Fosker N., Fraser A., Harris D.E., Larke N., Murphy L.D., Humphray S., O'Neil S., Pertea M., Price C., Rabbinowitsch E., Rajandream M.A., Salzberg S.L., Saunders D., Seeger K., Sharp S., Warren T., Denning D.W., Barrell B.G., Hall N.;
"Insight into the genome of Aspergillus fumigatus: analysis of a 922 kb region encompassing the nitrate assimilation gene cluster.";
Fungal Genet. Biol. 41:443-453(2004).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Af293 / CBS 101355 / FGSC A1100;
DOI=10.1038/nature04332; PubMed=16372009 [NCBI, ExPASy, EBI, Israel, Japan]
Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L., Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N., Barrell B.G., Denning D.W.;
"Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus.";
Nature 438:1151-1156(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL683874; CAD27295.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BX649605; CAE47942.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAHF01000004; EAL90545.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_752583.1; -.
3D structure databases
ModBase Q8TGG8.
Ontologies
GO
GO:0000139; Cellular component: Golgi membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0004382; Molecular function: guanosine-diphosphatase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR000407; GDA1_CD39_NTPase.
IPR015605; Gda1p.
Graphical view of domain structure.
PANTHER PTHR11782; GDA1_CD39_NTPase; 1.
PTHR11782:SF9; Gda1p; 1.
Pfam PF01150; GDA1_CD39; 1.
Pfam graphical view of domain structure.
PROSITE PS01238; GDA1_CD39_NTPASE; 1.
ProtoNet Q8TGG8.
Genome annotation databases
GeneID 3510633; -.
KEGG afm:AFUA_1G12150; -.
Phylogenomic databases
HOGENOM Q8TGG8; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycoprotein; Golgi apparatus; Hydrolase; Membrane; Signal-anchor; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   503  503     Probable guanosine-diphosphatase. PRO_0000209915
TOPO_DOM   1     8  8     Cytoplasmic (Potential). 
TRANSMEM   9    26  18     Signal-anchor for type II membrane protein (Potential). 
TOPO_DOM   27   503  477     Lumenal (Potential). 
CARBOHYD   318   318        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 503 AA [This is the length of the unprocessed precursor] Molecular weight: 55250 Da [This is the MW of the unprocessed precursor] CRC64: E49D642FA86CA04D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAQTQRSRYL KTGAIVAALL LMLLWISPSR PMHPSFPQGQ PSTSAPAKGK CSKPHDPKKP 

        70         80         90        100        110        120 
LIQYALMIDA GSQGSRIHVY RFNNCGPSPE LEDEVFFQTE PKKGGSGLSS YKEDAEGAAK 

       130        140        150        160        170        180 
SLDPLMEVAM KNVPDEYKSC SPIAVKATAG LRMLGPELSQ KILDAVRNRL ETVYPFPVVS 

       190        200        210        220        230        240 
KEKGGVEIMD GSDEGVYAWI TTNYLLGKIG GPDETPTAAV FDLGGGSTQI VFQPTFPKSK 

       250        260        270        280        290        300 
SGGMPERLSE GDHKYDLQFG GRHFELYQHS HLGYGLMAAR KAIHTSIIEN MLASSPKDLS 

       310        320        330        340        350        360 
WLKQPIPNPC IGPEMEKNVT LEFPEGHKLA PEVQVTMVGP KVGSTAAQCR GLAEKTLNKE 

       370        380        390        400        410        420 
AACTLAPCSF NGVHQPSLEK TFAREDVYIF SYFYDRTKPL GMPDSFTLDE LHQLTSTVCG 

       430        440        450        460        470        480 
GEDSWGIFAG IEGALKELRD RPEWCLDLNF MMSLLHTGYE MPLSREVKIA KKIKNRELGW 

       490        500 
CLGASLPLLS QESGWTCRIK EVS 

Q8TGG8 in FASTA format

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