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UniProtKB/Swiss-Prot entry Q8TA03


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 6PGD_DICDI
Primary accession number Q8TA03
Secondary accession number Q54YT0
Integrated into Swiss-Prot on April 8, 2008
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 36)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
Name: gnd
Synonyms: PGD
ORFNames: DDB_0215011
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/S0960-9822(01)00649-2; PubMed=11818061 [NCBI, ExPASy, EBI, Israel, Japan]
Andersson J.O., Roger A.J.;
"A cyanobacterial gene in nonphotosynthetic protists -- an early chloroplast acquisition in eukaryotes?";
Curr. Biol. 12:115-119(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF394516; AAL76326.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAFI02000023; EAL68115.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_642122.1; -.
3D structure databases
HSSP P00349; 2PGD. [HSSP ENTRY / PDB]
ModBase Q8TA03.
Organism-specific databases
dictyBase DDB0215011; gnd.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS Q8TA03.
Genome annotation databases
GeneID 3393571; -.
KEGG ddi:DDB_0215011; -.
Other
ProtoNet Q8TA03.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   493  493     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000327487
Sequence information
Length: 493 AA [This is the length of the unprocessed precursor] Molecular weight: 53891 Da [This is the MW of the unprocessed precursor] CRC64: C3FD8A0F07DFC688 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTEAKGDIGL IGLAVMGENL VLNMESRGFT CSVYNRTTSK VDEFVQGRGK GKKFIGCHSL 

        70         80         90        100        110        120 
ETLVQSLKTP RRVMLMVKAG EVVDHFIQLL LPLLEKGDII IDGGNSLYTD SDRRTKDLDA 

       130        140        150        160        170        180 
KGILFIGTGV SGGEEGALLG PSIMPGGNPK AWEHVKPIFQ AISAKVQPGD QPCCDWVGDG 

       190        200        210        220        230        240 
GAGHYVKMVH NGIEYGDMQL ISEAYFILKH YLGLSNDELQ KTFAKWNTGD LDSYLIEITA 

       250        260        270        280        290        300 
DIFAKKCEKD PNTYVVDTIL DSAGQKGTGK WTAINALDVG IPLTLVAESV FARCVSSFKE 

       310        320        330        340        350        360 
ERVKASTILA GPNPNEANKK FTGDKEQVIE AVRQALFASK LVSYAQGFTM MKAAAKEYKW 

       370        380        390        400        410        420 
NLNYGNIALL WRGGCIIRST FLGEIKGAFD KNPQLDNLLT DCWFRDKLAA AQDGWRQVAS 

       430        440        450        460        470        480 
ISVLHGIPTP AFTSALSYYD SYRCAKLSAN LVQAQRDYFG AHTFQLLDDP KGAPVHVNWT 

       490 
GRGGSTHSTT YSI 

Q8TA03 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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