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UniProtKB/Swiss-Prot entry Q8T1G5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LYSC_DICDI
Primary accession number Q8T1G5
Secondary accession number Q554H1
Integrated into Swiss-Prot on February 5, 2008
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 25)
Name and origin of the protein
Protein name Lysozyme C [Precursor]
Synonyms EC 3.2.1.17
1,4-beta-N-acetylmuramidase C
Gene name
Name: alyC
ORFNames: DDB_G0275121
From
Dictyostelium discoideum (Slime mold) [TaxID: 44689] 
Taxonomy Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature00847; PubMed=12097910 [NCBI, ExPASy, EBI, Israel, Japan]
Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T., Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R., Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A., Noegel A.A.;
"Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
Nature 418:79-85(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AX4;
DOI=10.1038/nature03481; PubMed=15875012 [NCBI, ExPASy, EBI, Israel, Japan]
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
"The genome of the social amoeba Dictyostelium discoideum.";
Nature 435:43-57(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC116305; AAM08433.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AAFI02000013; EAL69841.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_643740.1; -.
3D structure databases
ModBase Q8T1G5.
Organism-specific databases
dictyBase DDB_G0275121; alyC.
Ontologies
GO
GO:0060205; Cellular component: cytoplasmic membrane-bounded vesicle lumen (inferred from electronic annotation from UniProtKB-SubCell).
GO:0003796; Molecular function: lysozyme activity (inferred from sequence or structural similarity from UniProtKB).
GO:0019835; Biological process: cytolysis (inferred from electronic annotation from UniProtKB-KW).
GO:0050830; Biological process: defense response to Gram-positive bacterium (inferred from sequence or structural similarity from UniProtKB).
GO:0009253; Biological process: peptidoglycan catabolic process (inferred by curator from dictyBase).
QuickGo view.
Family and domain databases
ProtoNet Q8T1G5.
Genome annotation databases
GeneID 3394890; -.
KEGG ddi:DDB_0231279; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Antibiotic; Antimicrobial; Bacteriolytic enzyme; Complete proteome; Cytoplasmic vesicle; Glycosidase; Hydrolase; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    19  19     By similarity. 
CHAIN   20   138  119     Lysozyme C. PRO_0000315918
PROPEP   139   181  43     By similarity. PRO_0000315919
Sequence information
Length: 181 AA [This is the length of the unprocessed precursor] Molecular weight: 19752 Da [This is the MW of the unprocessed precursor] CRC64: 6160694D7857939C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MRIAFFLLIL SIIVGLAYGY SCPKPCYGNM CCSTSPDHKY YLTDFCGSTS ACGPKPSCSG 

        70         80         90        100        110        120 
KLYFTADSQR FGCGKHLNLC RGKKCVKAKV YDAGPAEWVE KDAGKMIIDA SPTICHELTG 

       130        140        150        160        170        180 
GSSCGWSDKF EITATVTSLT DSRPLGPFNV TEEEMDQLFI DHEIAMAQCE AEKTCNGFDL 


E 

Q8T1G5 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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NPSA logo NPSA Sequence analysis tools

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