NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PUTATIVE FUNCTION.
STRAIN=W23;
PubMed=11882717 [NCBI, ExPASy, EBI, Israel, Japan]
Lazarevic V., Abellan F.-X., Beggah Moeller S., Karamata D., Maueel C.;
"Comparison of ribitol and glycerol teichoic acid genes in Bacillus subtilis W23 and 168: identical function, similar divergent organization, but different regulation.";
Microbiology 148:815-824(2002).

Comments

FUNCTION: Provides activated ribitol phosphate for teichoic acid synthesis (Potential).
CATALYTIC ACTIVITY: CTP + D-ribitol 5-phosphate = diphosphate + CDP-ribitol.
PATHWAY: Cell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis .
SIMILARITY: Belongs to the ispD family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AJ313428; CAC86109.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

ModBase

Q8RKI9.

Ontologies

GO:0050518;	Molecular function: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0047349;	Molecular function: D-ribitol-5-phosphate cytidylyltransferase activity (inferred from electronic annotation from EC).
GO:0019350;	Biological process: teichoic acid biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
GO:0016114;	Biological process: terpenoid biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00108; atypical; 1.
PBIL [Tree]

InterPro

IPR001228; ISPD_synthase.
Graphical view of domain structure.

Pfam

PF01128; IspD; 1.
Pfam graphical view of domain structure.

PS01295; ISPD; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cell wall biogenesis/degradation; Nucleotidyltransferase; Teichoic acid biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 237`	`237`		`Putative ribitol-5-phosphate cytidylyltransferase.`	`PRO_0000075685`

Sequence information

Length: 237 AA [This is the length of the unprocessed precursor]

Molecular weight: 26848 Da [This is the MW of the unprocessed precursor]

CRC64: 0B03F2F41D6CE5AB [This is a checksum on the sequence]

        10         20         30         40         50         60 
MIYAEILAGG KGSRMGNVNM PKQFLPLNKR PIIIHTVEKF LLNDRFDKIL IVSPKEWINH 

        70         80         90        100        110        120 
TKDILKKFIG QDDRLVVVEG GSDRNESIMS GIRYIEKEFG IQDNDVIITH DSVRPFLTHR 

       130        140        150        160        170        180 
IIDENIDAVL QYGAVDTVIS AIDTIIASED QEFISDIPVR DNMYQGQTPQ SFRISKLVEL 

       190        200        210        220        230 
YNKLSDEQKA VLTDACKICS LAGEKVKLVR GEVFNIKVTT PYDLKVANAI LQERISQ

Q8RKI9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools