NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROBABLE FUNCTION.
STRAIN=W23;
PubMed=11882717 [NCBI, ExPASy, EBI, Israel, Japan]
Lazarevic V., Abellan F.-X., Beggah Moeller S., Karamata D., Maueel C.;
"Comparison of ribitol and glycerol teichoic acid genes in Bacillus subtilis W23 and 168: identical function, similar divergent organization, but different regulation.";
Microbiology 148:815-824(2002).

Comments

FUNCTION: Provides activated glycerol phosphate for teichoic acid synthesis, via incorporation into the linkage unit by tarB and tarF (Probable).
CATALYTIC ACTIVITY: CTP + sn-glycerol 3-phosphate = diphosphate + CDP-glycerol.
COFACTOR: Divalent metal cations. Prefers cobalt, magnesium, manganese or iron (By similarity).
PATHWAY: Cell wall biogenesis; poly(ribitol phosphate) teichoic acid biosynthesis .
SUBUNIT: Homodimer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the cytidylyltransferase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AJ313428; CAC86112.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P27623; 1COZ. [HSSP ENTRY / PDB]

SMR

Q8RKI6; 1-126.

ModBase

Q8RKI6.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0050897;	Molecular function: cobalt ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0047348;	Molecular function: glycerol-3-phosphate cytidylyltransferase activity (inferred from electronic annotation from InterPro).
GO:0005506;	Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0000287;	Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0030145;	Molecular function: manganese ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0019350;	Biological process: teichoic acid biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR004821; Cyt_trans_rel.
IPR004820; Cytidylyltransf.
IPR006409; G3P_cytidyltrfase.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.

Pfam

PF01467; CTP_transf_2; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00125; cyt_tran_rel; 1.
TIGR01518; g3p_cytidyltrns; 1.

ProtoNet

Q8RKI6.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cell wall biogenesis/degradation; Cobalt; Cytoplasm; Iron; Magnesium; Manganese; Nucleotidyltransferase; Teichoic acid biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 129`	`129`	`Glycerol-3-phosphate cytidylyltransferase.`	`PRO_0000208467`
`ACT_SITE`	`14 14`		`By similarity.`
`ACT_SITE`	`17 17`		`By similarity.`

Sequence information

Length: 129 AA [This is the length of the unprocessed precursor]

Molecular weight: 15257 Da [This is the MW of the unprocessed precursor]

CRC64: F2317D5F8A00247E [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKKVITYGTF DLFHYGHMKL LERAKNLGDY LIVGLSTDEF NLQKQKKSHH SYEHRKFILE 

        70         80         90        100        110        120 
TIDLVNEVIP EKNWEQKISD IQKHDIDTFV IGDDWKGKFD FLKEYCEVIY LPRTDGISTT 


QIKKDMASL

Q8RKI6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools