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UniProtKB/Swiss-Prot entry Q8RFG1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HUTI_FUSNN
Primary accession number Q8RFG1
Secondary accession numbers None
Integrated into Swiss-Prot on August 30, 2002
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 45)
Name and origin of the protein
Protein name Imidazolonepropionase
Synonyms EC 3.5.2.7
Imidazolone-5-propionate hydrolase
Gene name
Name: hutI
OrderedLocusNames: FN0740
From
Fusobacterium nucleatum subsp. nucleatum [TaxID: 76856] [HAMAP proteome]
Taxonomy Bacteria; Fusobacteria; Fusobacteriales; Fusobacteriaceae; Fusobacterium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131;
DOI=10.1128/JB.184.7.2005-2018.2002; PubMed=11889109 [NCBI, ExPASy, EBI, Israel, Japan]
Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A., Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O., Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M., Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N.C., Overbeek R.;
"Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum strain ATCC 25586.";
J. Bacteriol. 184:2005-2018(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE009951; AAL94936.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_603637.1; -.
3D structure databases
ModBase Q8RFG1.
Enzyme and pathway databases
BioCyc FNUC190304:FN0740-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0050480; Molecular function: imidazolonepropionase activity (inferred from electronic annotation from HAMAP).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0019556; Biological process: histidine catabolic process to glutamate and formamide (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00372; -; 1.
PBIL [Tree]
InterPro IPR006680; Amidohydro_1.
IPR005920; HutI.
Graphical view of domain structure.
Pfam PF01979; Amidohydro_1; 1.
Pfam graphical view of domain structure.
ProDom PD001248; Amidohydro_like; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01224; hutI; 1.
ProtoNet Q8RFG1.
Genome annotation databases
GeneID 991822; -.
GenomeReviews AE009951_GR; FN0740.
KEGG fnu:FN0740; -.
NMPDR fig|190304.1.peg.1316; -.
Phylogenomic databases
HOGENOM Q8RFG1; -.
Genome annotation databases
CMR Q8RFG1; FN0740.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Histidine metabolism; Hydrolase; Iron; Metal-binding; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   413  413     Imidazolonepropionase. PRO_0000160948
METAL   79    79        Zinc or iron (By similarity). 
METAL   81    81        Zinc or iron (By similarity). 
METAL   248   248        Zinc or iron (By similarity). 
METAL   322   322        Zinc or iron (By similarity). 
BINDING   88    88        Substrate (By similarity). 
BINDING   101   101        Substrate (By similarity). 
BINDING   151   151        Substrate (By similarity). 
BINDING   184   184        Substrate (By similarity). 
BINDING   251   251        Substrate (By similarity). 
Sequence information
Length: 413 AA [This is the length of the unprocessed precursor] Molecular weight: 45367 Da [This is the MW of the unprocessed precursor] CRC64: F14316699227C27D [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MQADLVLYNI GQLVTSRELD KTKKMDNIEV IENNGYIVIE KDKIVAVGSG EVLKEYLTPA 

        70         80         90        100        110        120 
TEMVDLSGKL VTPGLIDSHT HLVHGGSREN EFAMKIAGVP YLEILEKGGG ILSTLKSTRN 

       130        140        150        160        170        180 
ASEQELIEKT LKSLRHMLEL GVTTVEAKSG YGLNLEDELK QLEVTKILGY LQPVTLVSTF 

       190        200        210        220        230        240 
MAAHATPPEY KDNKEGYVQE VIKMLPIVKE RNLAEFCDIF CEDKVFSVDE SRRILTVAKE 

       250        260        270        280        290        300 
LGYKLKIHAD EIVSLGGVEL AAELGATSAE HLMKITDSGI NALANSNVIA DLLPATSFNL 

       310        320        330        340        350        360 
MEHYAPARKM IEAGIQIALS TDYNPGSCPS ENLQFVMQIG AAHLKMTPKE VFKSVTINAA 

       370        380        390        400        410 
KAIDKQDTIG SIEVGKKADI TVFDAPSMAY FLYHFGINHT DSVYKNGKLV FKK
Q8RFG1 in FASTA format

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