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UniProtKB/Swiss-Prot entry Q8REA7

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NADE_FUSNN
Primary accession number Q8REA7
Secondary accession numbers None
Integrated into Swiss-Prot on November 15, 2002
Sequence was last modified on June 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 38)
Name and origin of the protein
Protein name NH(3)-dependent NAD(+) synthetase
Synonym EC 6.3.1.5
Gene name
Name: nadE
OrderedLocusNames: FN1202
From
Fusobacterium nucleatum subsp. nucleatum [TaxID: 76856] [HAMAP proteome]
Taxonomy Bacteria; Fusobacteria; Fusobacteriales; Fusobacteriaceae; Fusobacterium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131;
DOI=10.1128/JB.184.7.2005-2018.2002; PubMed=11889109 [NCBI, ExPASy, EBI, Israel, Japan]
Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A., Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O., Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M., Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N.C., Overbeek R.;
"Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum strain ATCC 25586.";
J. Bacteriol. 184:2005-2018(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE009951; AAL95398.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_604099.1; -.
3D structure databases
HSSP P08164; 1IH8. [HSSP ENTRY / PDB]
ModBase Q8REA7.
Enzyme and pathway databases
BioCyc FNUC190304:FN1202-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0003952; Molecular function: NAD+ synthase (glutamine-hydrolyzing) activity (inferred from electronic annotation from InterPro).
GO:0008795; Molecular function: NAD+ synthase activity (inferred from electronic annotation from EC).
GO:0009435; Biological process: NAD biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00193; -; 1.
PBIL [Tree]
InterPro IPR003694; NAD_synthase.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
Pfam PF02540; NAD_synthase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00552; nadE; 1.
ProtoNet Q8REA7.
Genome annotation databases
GeneID 991988; -.
GenomeReviews AE009951_GR; FN1202.
KEGG fnu:FN1202; -.
NMPDR fig|190304.1.peg.1778; -.
Phylogenomic databases
HOGENOM Q8REA7; -.
Genome annotation databases
CMR Q8REA7; FN1202.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Ligase; NAD; Nucleotide-binding.
Features
SEVIEWER logo Feature table viewer
KeyFrom  To Length Description FTId
CHAIN   1   258  258     NH(3)-dependent NAD(+) synthetase. PRO_0000152171
NP_BIND   34    41  8     ATP (By similarity). 
ACT_SITE   36    36        By similarity. 
Sequence information
Length: 258 AA [This is the length of the unprocessed precursor] Molecular weight: 29493 Da [This is the MW of the unprocessed precursor] CRC64: 760CEC7C9A7D517B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNKLDLNLKE VHNELVEFLR ENFKKAGFSK AVLGLSGGID SALVAYLLRD ALGKENVLAI 

        70         80         90        100        110        120 
MMPYKSSNPD SLNHAKLVVE DLKINSKTIE ITDMIDAYFK NEKEATSLRM GNKMARERMS 

       130        140        150        160        170        180 
ILFDYSSKEN ALVVGTSNKT EIYLGYSTQF GDAACALNPI GDLYKTNIWD LSRYLKIPNE 

       190        200        210        220        230        240 
LIEKKPSADL WEGQTDEQEM GLTYKEADQV MYRLLEENKT VEEVLAEGFN KDLVDNIVRR 

       250 
MNRSEYKRRM PLIAKIKR
Q8REA7 in FASTA format

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