NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11883 / OCM 88;
PubMed=12125824 [NCBI, ExPASy, EBI, Israel, Japan]
Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A., Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C., Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S., Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P., Fritz H.-J., Gottschalk G.;
"The genome of Methanosarcina mazei: evidence for lateral gene transfer between Bacteria and Archaea.";
J. Mol. Microbiol. Biotechnol. 4:453-461(2002).

Comments

CATALYTIC ACTIVITY: ATP + nicotinamide ribonucleotide = diphosphate + NAD⁺.
PATHWAY: Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide ribonucleotide: step 1/1 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the archaeal NMN adenylyltransferase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AE008384; AAM30322.1; ALT_INIT; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_632650.1; -.

3D structure databases

HSSP

Q57961; 1F9A. [HSSP ENTRY / PDB]

ModBase

Q8PZ68.

Enzyme and pathway databases

BioCyc

MMAZ192952:MM0626-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0000309;	Molecular function: nicotinamide-nucleotide adenylyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0009435;	Biological process: NAD biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00243; -; 1.
PBIL [Tree]

InterPro

IPR004821; Cyt_trans_rel.
IPR004820; Cytidylyltransf.
IPR006418; NMN_Atrans_arc.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.

Pfam

PF01467; CTP_transf_2; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR01527; arch_NMN_Atrans; 1.
TIGR00125; cyt_tran_rel; 1.

ProtoNet

Q8PZ68.

Genome annotation databases

GeneID

1478968; -.

GenomeReviews

AE008384_GR; MM_0626.

KEGG

mma:MM_0626; -.

NMPDR

fig|192952.1.peg.626; -.

Phylogenomic databases

HOGENOM

Q8PZ68; -.

Genome annotation databases

CMR

Q8PZ68; MM_0626.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; NAD; Nucleotidyltransferase; Pyridine nucleotide biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 173`	`173`		`Nicotinamide-nucleotide adenylyltransferase.`	`PRO_0000134993`

Sequence information

Length: 173 AA [This is the length of the unprocessed precursor]

Molecular weight: 19970 Da [This is the MW of the unprocessed precursor]

CRC64: D8D7EE0C6640B3D8 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTRAFYIGRF QPYHFGHHAV IARIAEEVDE LVIGIGSAQK SHEAIDPFTA GERVLMVYNA 

        70         80         90        100        110        120 
LEHLSIRHYV VPIEDVRYNS IWVHHVVSRT PRFDVVYSNN PLVIQLFREA GFCVKESPLY 

       130        140        150        160        170 
VRERYSGTEI RRRMIEGEKW EHLVPKPVAE VIKSFDGVSR LKNVSTSDSN FSL

Q8PZ68 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools