ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q8PQ74

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name HGD_XANAC
Primary accession number Q8PQ74
Secondary accession numbers None
Integrated into Swiss-Prot on October 10, 2002
Sequence was last modified on October 10, 2002 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 39)
Name and origin of the protein
Protein name Homogentisate 1,2-dioxygenase
Synonyms EC 1.13.11.5
Homogentisicase
Homogentisate oxygenase
Homogentisic acid oxidase
Gene name
Name: hmgA
OrderedLocusNames: XAC0454
From
Xanthomonas axonopodis pv. citri (Citrus canker) [TaxID: 92829] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales; Xanthomonadaceae; Xanthomonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=306;
DOI=10.1038/417459a; PubMed=12024217 [NCBI, ExPASy, EBI, Israel, Japan]
da Silva A.C.R., Ferro J.A., Reinach F.C., Farah C.S., Furlan L.R., Quaggio R.B., Monteiro-Vitorello C.B., Van Sluys M.A., Almeida N.F. Jr., Alves L.M.C., do Amaral A.M., Bertolini M.C., Camargo L.E.A., Camarotte G., Cannavan F., Cardozo J., Chambergo F., Ciapina L.P., Cicarelli R.M.B., Coutinho L.L., Cursino-Santos J.R., El-Dorry H., Faria J.B., Ferreira A.J.S., Ferreira R.C.C., Ferro M.I.T., Formighieri E.F., Franco M.C., Greggio C.C., Gruber A., Katsuyama A.M., Kishi L.T., Leite R.P., Lemos E.G.M., Lemos M.V.F., Locali E.C., Machado M.A., Madeira A.M.B.N., Martinez-Rossi N.M., Martins E.C., Meidanis J., Menck C.F.M., Miyaki C.Y., Moon D.H., Moreira L.M., Novo M.T.M., Okura V.K., Oliveira M.C., Oliveira V.R., Pereira H.A., Rossi A., Sena J.A.D., Silva C., de Souza R.F., Spinola L.A.F., Takita M.A., Tamura R.E., Teixeira E.C., Tezza R.I.D., Trindade dos Santos M., Truffi D., Tsai S.M., White F.F., Setubal J.C., Kitajima J.P.;
"Comparison of the genomes of two Xanthomonas pathogens with differing host specificities.";
Nature 417:459-463(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE011672; AAM35345.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_640809.1; -.
3D structure databases
ModBase Q8PQ74.
Enzyme and pathway databases
BioCyc XAXO190486:XAC0454-MON; -.
Ontologies
GO
GO:0004411; Molecular function: homogentisate 1,2-dioxygenase activity (inferred from electronic annotation from HAMAP).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from HAMAP).
GO:0006559; Biological process: L-phenylalanine catabolic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006572; Biological process: tyrosine catabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00334; -; 1.
PBIL [Tree]
InterPro IPR005708; Homogentis_dOase.
Graphical view of domain structure.
PANTHER PTHR11056; Homogentis_dOase; 1.
Pfam PF04209; HgmA; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01015; hmgA; 1.
ProtoNet Q8PQ74.
Genome annotation databases
GeneID 1154525; -.
GenomeReviews AE008923_GR; XAC0454.
KEGG xac:XAC0454; -.
NMPDR fig|190486.1.peg.453; -.
Phylogenomic databases
HOGENOM Q8PQ74; -.
Genome annotation databases
CMR Q8PQ74; XAC0454.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Phenylalanine catabolism; Tyrosine catabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   458  458     Homogentisate 1,2-dioxygenase. PRO_0000220257
METAL   351   351        Iron (By similarity). 
METAL   357   357        Iron (By similarity). 
METAL   387   387        Iron (By similarity). 
Sequence information
Length: 458 AA [This is the length of the unprocessed precursor] Molecular weight: 50450 Da [This is the MW of the unprocessed precursor] CRC64: E2237A2256088FDD [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MIQRDPNLLL SWRADQHPDA PMHNDQRYMT GFGNEFATEA VAGSLPIGQN SPQRVAHGLY 

        70         80         90        100        110        120 
AEQLSGTAFT APRGQNRRSW LYRIRPAAVH GSFSLVEQSH FHNDFGAGPV PPDQLRWSPL 

       130        140        150        160        170        180 
PLPSVPTDFV DGLYTMAGNG GPEAMSGVGV HVYAANASMQ DRFFYDADGE LLLVPQQGRL 

       190        200        210        220        230        240 
RVHTELGVLA LEPQQIGVIP RGMRFRVELL DAAARGYVCE NFGGLLRLPD LGPIGANGLA 

       250        260        270        280        290        300 
NPRDFETPHA AFEQREGTFE LVAKFQGHLW RADIGHSPLD VVAWHGNYAP YRYDLRRFNT 

       310        320        330        340        350        360 
IGSISFDHPD PSIFTVLTSP SDTHGTANMD FAIFPPRWLV AQHTFRPPWF HRNVASEFMG 

       370        380        390        400        410        420 
LVHGVYDAKA EGFAPGGASL HNCMSGHGPD AATFDKASQA DLTRPDVIAD TMAFMFETRA 

       430        440        450 
VLRPTQQALS AAHRQADYQQ CWSGLRAAFQ PPITEDAT
Q8PQ74 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!