ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q8NWU6

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name TYRA_STAAW
Primary accession number Q8NWU6
Secondary accession numbers None
Integrated into Swiss-Prot on April 3, 2007
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 33)
Name and origin of the protein
Protein name Prephenate dehydrogenase
Synonyms PDH
EC 1.3.1.12
Gene name
Name: tyrA
OrderedLocusNames: MW1252
From
Staphylococcus aureus (strain MW2) [TaxID: 196620] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 4: Predicted;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/S0140-6736(02)08713-5; PubMed=12044378 [NCBI, ExPASy, EBI, Israel, Japan]
Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y., Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
"Genome and virulence determinants of high virulence community-acquired MRSA.";
Lancet 359:1819-1827(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000033; BAB95117.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_646069.1; -.
3D structure databases
ModBase Q8NWU6.
Enzyme and pathway databases
BioCyc SAUR196620:MW1252-MON; -.
Ontologies
GO
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0004665; Molecular function: prephenate dehydrogenase (NADP+) activity (inferred from electronic annotation from InterPro).
GO:0008977; Molecular function: prephenate dehydrogenase activity (inferred from electronic annotation from EC).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
GO:0006571; Biological process: tyrosine biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR003099; Prephen_DHase.
Graphical view of domain structure.
PANTHER PTHR21363; Prephen_DH; 1.
Pfam PF02153; PDH; 1.
Pfam graphical view of domain structure.
PROSITE PS51176; PDH_ADH; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet Q8NWU6.
Genome annotation databases
GeneID 1003364; -.
GenomeReviews BA000033_GR; MW1252.
KEGG sam:MW1252; -.
Phylogenomic databases
HOGENOM Q8NWU6; -.
Genome annotation databases
CMR Q8NWU6; MW1252.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NAD; Oxidoreductase; Tyrosine biosynthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom To Length Description FTId
CHAIN   1   363  363     Prephenate dehydrogenase. PRO_0000282659
DOMAIN   2   291  290     Prephenate/arogenate dehydrogenase. 
NP_BIND   3    33  31     NAD (Potential). 
Sequence information
Length: 363 AA [This is the length of the unprocessed precursor] Molecular weight: 40395 Da [This is the MW of the unprocessed precursor] CRC64: 8F16333DC3B816C6 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MTTVLFVGLG LIGGSLASNI KYHNPNTNII AYDADTSQLD KAKSIGIINE KCLNYSEAIK 

        70         80         90        100        110        120 
KADVIIYATP VAITNKYLSE LIDMPTKPGV IVSDTGSTKA MIQQHECNLL KHNIHLVSGH 

       130        140        150        160        170        180 
PMAGSHKSGV LNAKKHLFEN AYYILVYNEP RNEQAANTLK ELLSPTLAKF IVTTAEEHDY 

       190        200        210        220        230        240 
VTSVVSHLPH IVASSLVHVS QKNGQEHHLV NKLAAGGFRD ITRIASSNAQ MWKDITLSNK 

       250        260        270        280        290        300 
TYILEMIRQL KSQFQDLERL IESNDSEKLL SFFAQAKSYR DALPAKQLGG LNTAYDLYVD 

       310        320        330        340        350        360 
IPDESGMISK VTYILSLHNI SISNLRILEV REDIYGALKI SFKNPTDRER GMQALSDFDC 


YIQ
Q8NWU6 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!