[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. TISSUE=Testis; DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan] The MGC Project Team; "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."; Genome Res. 14:2121-2127(2004).
[2]	STRUCTURE BY NMR OF 1-82. RIKEN structural genomics initiative (RSGI); "Solution structure of the J domain of DnaJ homolog subfamily B member 8."; Submitted (OCT-2006) to the PDB data bank.

Comments

SIMILARITY: Contains 1 J domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BC029521; AAH29521.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
BC050288; AAH50288.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_699161.1; -.

UniGene

Hs.518241

3D structure databases

PDB

2DMX; NMR; -; A=1-82.

[ExPASy / RCSB / EBI]

PDBsum

2DMX; -.

ModBase

Q8NHS0.

Organism-specific databases

HGNC:23699; DNAJB8.

611337; gene. [NCBI / EBI]

PharmGKB

PA134881798; -.

GeneCards

Q8NHS0.

Gene expression databases

ArrayExpress

Q8NHS0; -.

CleanEx

HS_DNAJB8; -.

GermOnline

ENSG00000179407; Homo sapiens.

Ontologies

GO:0031072;	Molecular function: heat shock protein binding (inferred from electronic annotation from InterPro).
QuickGo view.

Family and domain databases

InterPro

IPR001623; DnaJ_N.
IPR015609; Hsp40/DnaJ_Rel.
Graphical view of domain structure.

Gene3D

G3DSA:1.10.287.110; DnaJ_N; 1.

PANTHER

PTHR11821; Hsp40/DnaJ_Rel; 1.

Pfam

PF00226; DnaJ; 1.
Pfam graphical view of domain structure.

SMART

SM00271; DnaJ; 1.
SMART graphical view of domain structure.

PROSITE

PS00636; DNAJ_1; 1.
PS50076; DNAJ_2; 1.
PROSITE graphical view of domain structure (profiles).

ProtoNet

Q8NHS0.

Genome annotation databases

Ensembl

ENSG00000179407; Homo sapiens. [Contig view]

GeneID

165721; -.

KEGG

hsa:165721; -.

Phylogenomic databases

HOGENOM

Q8NHS0; -.

HOVERGEN

Q8NHS0; -.

Other

LinkHub

Q8NHS0; -.

NextBio

88560; -.

SOURCE

DNAJB8; Homo sapiens.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

3D-structure; Chaperone; Polymorphism.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 232`	`232`	`DnaJ homolog subfamily B member 8.`	`PRO_0000071029`
`DOMAIN`	`3 69`	`67`	`J.`
`VARIANT`	`153 153`	`1`	`M -> L (in dbSNP:rs35948511 [NCBI]).`	`VAR_033881`

Sequence information

Length: 232 AA [This is the length of the unprocessed precursor]

Molecular weight: 25686 Da [This is the MW of the unprocessed precursor]

CRC64: 058B180995B772F6 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MANYYEVLGV QASASPEDIK KAYRKLALRW HPDKNPDNKE EAEKKFKLVS EAYEVLSDSK 

        70         80         90        100        110        120 
KRSLYDRAGC DSWRAGGGAS TPYHSPFDTG YTFRNPEDIF REFFGGLDPF SFEFWDSPFN 

       130        140        150        160        170        180 
SDRGGRGHGL RGAFSAGFGE FPAFMEAFSS FNMLGCSGGS HTTFSSTSFG GSSSGSSGFK 

       190        200        210        220        230 
SVMSSTEMIN GHKVTTKRIV ENGQERVEVE EDGQLKSVTV NGKEQLKWMD SK

Q8NHS0 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools