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UniProtKB/Swiss-Prot entry Q8LG50


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LPAT2_ARATH
Primary accession number Q8LG50
Secondary accession number Q9SVX9
Integrated into Swiss-Prot on May 10, 2005
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 4, 2008 (Entry version 34)
Name and origin of the protein
Protein name 1-acyl-sn-glycerol-3-phosphate acyltransferase 2
Synonyms EC 2.3.1.51
Lysophosphatidyl acyltransferase 2
Gene name
Name: LPAT2
Synonyms: LPAAT2
OrderedLocusNames: At3g57650
ORFNames: F15B8.160
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048706; PubMed=11130713 [NCBI, ExPASy, EBI, Israel, Japan]
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
Nature 408:820-822(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[3]
TISSUE SPECIFICITY.
DOI=10.1104/pp.103.035832; PubMed=14976237 [NCBI, ExPASy, EBI, Israel, Japan]
Kim H.U., Huang A.H.C.;
"Plastid lysophosphatidyl acyltransferase is essential for embryo development in Arabidopsis.";
Plant Physiol. 134:1206-1216(2004).
[4]
FUNCTION, ENZYME ACTIVITY, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
DOI=10.1105/tpc.104.030403; PubMed=15772283 [NCBI, ExPASy, EBI, Israel, Japan]
Kim H.U., Li Y., Huang A.H.C.;
"Ubiquitous and endoplasmic reticulum-located lysophosphatidyl acyltransferase, LPAT2, is essential for female but not male gametophyte development in Arabidopsis.";
Plant Cell 17:1073-1089(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL049660; CAB41190.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY084461; AAM61033.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T06755; T06755.
3D structure databases
ModBase Q8LG50.
Organism-specific databases
TAIR At3g57650; -.
Gene expression databases
GermOnline AT3G57650; Arabidopsis thaliana.
Ontologies
GO
GO:0005789; Cellular component: endoplasmic reticulum membrane (inferred from electronic annotation from UniProtKB-SubCell).
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0003841; Molecular function: 1-acylglycerol-3-phosphate O-acyltransferase activity (inferred from electronic annotation from EC).
GO:0007275; Biological process: multicellular organismal development (inferred from electronic annotation from UniProtKB-KW).
GO:0008654; Biological process: phospholipid biosynthetic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR002123; Acyltransferase.
Graphical view of domain structure.
Pfam PF01553; Acyltransferase; 1.
Pfam graphical view of domain structure.
SMART SM00563; PlsC; 1.
SMART graphical view of domain structure.
ProtoNet Q8LG50.
Genome annotation databases
GenomeReviews BA000014_GR; AT3G57650.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Acyltransferase; Complete proteome; Developmental protein; Endoplasmic reticulum; Membrane; Phospholipid biosynthesis; Transferase; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   389  389     1-acyl-sn-glycerol-3-phosphate acyltransferase 2. PRO_0000208179
TRANSMEM   2    22  21     Potential. 
TRANSMEM   305   325  21     Potential. 
TRANSMEM   333   353  21     Potential. 
MOTIF   91    96  6     HXXXXD motif. 
Sequence information
Length: 389 AA [This is the length of the unprocessed precursor] Molecular weight: 43706 Da [This is the MW of the unprocessed precursor] CRC64: F34F73B2E2AC6837 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MVIAAAVIVP LGLLFFISGL AVNLFQAVCY VLIRPLSKNT YRKINRVVAE TLWLELVWIV 

        70         80         90        100        110        120 
DWWAGVKIQV FADNETFNRM GKEHALVVCN HRSDIDWLVG WILAQRSGCL GSALAVMKKS 

       130        140        150        160        170        180 
SKFLPVIGWS MWFSEYLFLE RNWAKDESTL KSGLQRLSDF PRPFWLALFV EGTRFTEAKL 

       190        200        210        220        230        240 
KAAQEYAASS ELPIPRNVLI PRTKSFVSAV SNMRSFVPAI YDMTVTIPKT SPPPTMLRLF 

       250        260        270        280        290        300 
KGQPSVVHVH IKCHSMKDLP ESDDAIAQWC RDQFVAKDAL LDKHIAADTF PGQQEQNIGR 

       310        320        330        340        350        360 
PIKSLAVVLS WACVLTLGAI KFLHWAQLFS SWKGITISAL GLGIITLCMQ ILIRSSQSER 

       370        380 
STPAKVVPAK PKDNHHPESS SQTETEKEK 

Q8LG50 in FASTA format

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