ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with beta.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q8LEA8


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name EID1_ARATH
Primary accession number Q8LEA8
Secondary accession numbers O81289 Q0WMI9
Integrated into Swiss-Prot on June 21, 2005
Sequence was last modified on June 21, 2005 (Sequence version 2)
Annotations were last modified on    May 20, 2008 (Entry version 41)
Name and origin of the protein
Protein name Phytochrome A-associated F-box protein
Synonym Empfindlicher im dunkelroten Licht protein 1
Gene name
Name: EID1
OrderedLocusNames: At4g02440
ORFNames: T14P8.22
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/47134; PubMed=10617198 [NCBI, ExPASy, EBI, Israel, Japan]
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.;
"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
Nature 402:769-777(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[5]
FUNCTION.
DOI=10.1105/tpc.12.4.547; PubMed=10760243 [NCBI, ExPASy, EBI, Israel, Japan]
Bueche C., Poppe C., Schaefer E., Kretsch T.;
"eid1: a new Arabidopsis mutant hypersensitive in phytochrome A-dependent high-irradiance responses.";
Plant Cell 12:547-558(2000).
[6]
SUBCELLULAR LOCATION, NUCLEAR LOCALIZATION SIGNAL, INTERACTION WITH SKP1A AND SKP1B, DOMAIN, AND MUTAGENESIS OF PRO-10; GLY-101 AND 197-ARG-LYS-198.
DOI=10.1101/gad.197201; PubMed=11316788 [NCBI, ExPASy, EBI, Israel, Japan]
Dieterle M., Zhou Y.-C., Schaefer E., Funk M., Kretsch T.;
"EID1, an F-box protein involved in phytochrome A-specific light signaling.";
Genes Dev. 15:939-944(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF069298; AAC19270.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL161494; CAB80737.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT002038; AAN72049.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT008731; AAP42744.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AK229833; BAF01662.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY085530; AAM62754.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T01306; T01306.
RefSeq NP_192153.1; -.
UniGene At.43977
3D structure databases
ModBase Q8LEA8.
Protein-protein interaction databases
IntAct Q8LEA8; -.
Organism-specific databases
TAIR At4g02440; -.
Gene expression databases
GermOnline AT4G02440; Arabidopsis thaliana.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR001810; F-box.
Graphical view of domain structure.
Pfam PF00646; F-box; 1.
Pfam graphical view of domain structure.
PROSITE PS50181; FBOX; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q8LEA8.
Genome annotation databases
GeneID 828008; -.
GenomeReviews CT486007_GR; AT4G02440.
KEGG ath:AT4G02440; -.
NMPDR fig|3702.1.peg.18057; -.
Other
ProtoNet Q8LEA8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Nucleus; Phytochrome signaling pathway; Ubl conjugation pathway.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   336  336     Phytochrome A-associated F-box protein. PRO_0000119961
DOMAIN   3    55  53     F-box. 
MOTIF   197   201  5     Nuclear localization signal. 
MUTAGEN   10    10        P->A: Disrupts interaction with SKP1A and SKP1B. 
MUTAGEN   101   101        G->C: In eid1-2; enhances sensitivity to red and far-red light. 
MUTAGEN   197   198        RK->SE: Cytoplasmic localization instead of nuclear. 
CONFLICT   16    16        N -> K (in Ref. 4; AAM62754). 
CONFLICT   71    71        A -> AA (in Ref. 4; AAM62754). 
Sequence information
Length: 336 AA [This is the length of the unprocessed precursor] Molecular weight: 37398 Da [This is the MW of the unprocessed precursor] CRC64: 0E4231CCF243487C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAESVFSCIP EDVVFNIFFK LQDDPRNWAR LACVCTKFSS IVRNVCCKTQ CYSAIPTVIS 

        70         80         90        100        110        120 
DLLPLPPSAA ASASSSTAAD SSLTPPGGWA SLYKLAVCCP GLFHAGILLE NSDFGLEREL 

       130        140        150        160        170        180 
GPDQNLDPKP TTTDLALNDE EVSKPVGSGL ETTSFWSLYD DLYTDTIPAP PPEDSIDDQE 

       190        200        210        220        230        240 
EEIETSEIRP GRDLPVRKRR KICRSLGSHL ASGGWNLSRE QGNKLLASRF RGDCLYICNW 

       250        260        270        280        290        300 
PGCIHVEEKR NYMLFRGVFK DFKRSRVWRT INDGNRSKTS GLKCAFCLCD ETWDLHSSFC 

       310        320        330 
LRRVFGFHDD GEPVVRAYVC ENGHVSGAWT ALPLYT 

Q8LEA8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
 Hosted by ch flag SIB Switzerland Mirror sites: Australia  Brazil  Canada  China  Korea
Notice: This page will be replaced with beta.uniprot.org. Please send us your feedback!