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UniProtKB/Swiss-Prot entry Q8LCP6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUN10_ARATH
Primary accession number Q8LCP6
Secondary accession number Q9LR07
Integrated into Swiss-Prot on September 5, 2006
Sequence was last modified on September 5, 2006 (Sequence version 2)
Annotations were last modified on    November 4, 2008 (Entry version 35)
Name and origin of the protein
Protein name Endoglucanase 10 [Precursor]
Synonyms EC 3.2.1.4
Endo-1,4-beta glucanase 10
Gene name
OrderedLocusNames: At1g75680
ORFNames: F10A5.13
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35048500; PubMed=11130712 [NCBI, ExPASy, EBI, Israel, Japan]
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.;
"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
Nature 408:816-820(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[4]
GENE FAMILY.
DOI=10.1007/s00239-003-2571-x; PubMed=15170254 [NCBI, ExPASy, EBI, Israel, Japan]
Libertini E., Li Y., McQueen-Mason S.J.;
"Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family.";
J. Mol. Evol. 58:506-515(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC006434; AAF87112.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY039938; AAK64042.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY150451; AAN12892.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY086475; AAM63477.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR E96786; E96786.
RefSeq NP_177697.1; -.
UniGene At.23725
3D structure databases
HSSP P26221; 1TF4. [HSSP ENTRY / PDB]
ModBase Q8LCP6.
Organism-specific databases
TAIR At1g75680; -.
Gene expression databases
GermOnline AT1G75680; Arabidopsis thaliana.
Ontologies
GO
GO:0005576; Cellular component: extracellular region (inferred from electronic annotation from UniProtKB-KW).
GO:0008810; Molecular function: cellulase activity (inferred from electronic annotation from EC).
GO:0007047; Biological process: cell wall organization (inferred from electronic annotation from UniProtKB-KW).
GO:0030245; Biological process: cellulose catabolic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR012341; 6hp_glycosidase.
IPR001701; Glyco_hydro_9.
Graphical view of domain structure.
Gene3D G3DSA:1.50.10.10; CelA/Cel48F_cat; 1.
PANTHER PTHR22298:SF3; Glyco_hydro_9; 1.
Pfam PF00759; Glyco_hydro_9; 1.
Pfam graphical view of domain structure.
PROSITE PS00592; GLYCOSYL_HYDROL_F9_1; 1.
PS00698; GLYCOSYL_HYDROL_F9_2; FALSE_NEG.
ProtoNet Q8LCP6.
Genome annotation databases
GeneID 843902; -.
GenomeReviews CT485782_GR; AT1G75680.
KEGG ath:AT1G75680; -.
NMPDR fig|3702.1.peg.7086; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Cell wall biogenesis/degradation; Cellulose degradation; Complete proteome; Glycoprotein; Glycosidase; Hydrolase; Polysaccharide degradation; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
SIGNAL   1    26  26     Potential. 
CHAIN   27   525  499     Endoglucanase 10. PRO_0000249262
ACT_SITE   442   442        By similarity. 
ACT_SITE   489   489        By similarity. 
ACT_SITE   498   498        By similarity. 
CARBOHYD   259   259        N-linked (GlcNAc...) (Potential). 
CARBOHYD   464   464        N-linked (GlcNAc...) (Potential). 
CARBOHYD   484   484        N-linked (GlcNAc...) (Potential). 
CONFLICT   45    45        G -> C (in Ref. 3; AAM63477). 
CONFLICT   238   238        N -> D (in Ref. 3; AAM63477). 
Sequence information
Length: 525 AA [This is the length of the unprocessed precursor] Molecular weight: 57868 Da [This is the MW of the unprocessed precursor] CRC64: FBC3704F4BB8BB71 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEEKSKSRGW CGWFIAIIVL ASVILAVVYT VKLRTKKSGD DDGGGPVPGP PGAIDKKYAD 

        70         80         90        100        110        120 
ALKLALQFFD IQKSGKLENN KIPWRGDSGL KDGSEDNLDL SKGLYDAGDH IKFGFPMAFT 

       130        140        150        160        170        180 
ATVLSWSILE YGDQMNAVNQ LDPAKDSLRW ITDYLIKAHP SDNVLYIQVG DPKVDHPCWE 

       190        200        210        220        230        240 
RPEDMKEKRP LTKIDVDTPG TEVAAETAAA MASASLVFKD SDPTYSATLL KHAKQLFNFA 

       250        260        270        280        290        300 
DTKRGSYSVN IPEVQKFYNS TGYGDELLWA ASWLYHATED KTYLDYVSNH GKEFASFGNP 

       310        320        330        340        350        360 
TWFSWDNKLA GTQVLLSRLL FFKKDLSGSK GLGNYRNTAK AVMCGLLPKS PTSTASRTNG 

       370        380        390        400        410        420 
GLIWVSEWNS MQQSVSSAFL ASLFSDYMLT SRIHKISCDG KIFKATELRD FAKSQADYML 

       430        440        450        460        470        480 
GKNPLGTSFV VGYGDKYPQF VHHRGASIPA DATTGCLDGF KWFNSTKPNP NIAYGALVGG 

       490        500        510        520 
PFFNETFTDS RENPMQNEPT TYNNALLVGL LSSLVTTSST LQSLK 

Q8LCP6 in FASTA format

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