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UniProtKB/Swiss-Prot entry Q8LAW2


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AFR_ARATH
Primary accession number Q8LAW2
Secondary accession number Q9SJB1
Integrated into Swiss-Prot on June 7, 2005
Sequence was last modified on June 7, 2005 (Sequence version 2)
Annotations were last modified on    April 29, 2008 (Entry version 38)
Name and origin of the protein
Protein name Protein AFR
Synonym Protein ATTENUATED FAR-RED RESPONSE
Gene name
Name: AFR
OrderedLocusNames: At2g24540
ORFNames: F25P17.16
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/45471; PubMed=10617197 [NCBI, ExPASy, EBI, Israel, Japan]
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
Nature 402:761-768(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[4]
INDUCTION.
DOI=10.1126/science.290.5499.2110; PubMed=11118138 [NCBI, ExPASy, EBI, Israel, Japan]
Harmer S.L., Hogenesch J.B., Straume M., Chang H.-S., Han B., Zhu T., Wang X., Kreps J.A., Kay S.A.;
"Orchestrated transcription of key pathways in Arabidopsis by the circadian clock.";
Science 290:2110-2113(2000).
[5]
FUNCTION, INDUCTION, AND INTERACTION WITH SKP1A.
DOI=10.1016/j.cub.2003.11.019; PubMed=14653999 [NCBI, ExPASy, EBI, Israel, Japan]
Harmon F.G., Kay S.A.;
"The F box protein AFR is a positive regulator of phytochrome A-mediated light signaling.";
Curr. Biol. 13:2091-2096(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC006954; AAD23891.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY072009; AAL57704.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT000847; AAN38684.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY087570; AAM65112.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR H84637; H84637.
RefSeq NP_565572.1; -.
UniGene At.28274
3D structure databases
ModBase Q8LAW2.
Protein-protein interaction databases
IntAct Q8LAW2; -.
Organism-specific databases
TAIR At2g24540; -.
Gene expression databases
GermOnline AT2G24540; Arabidopsis thaliana.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR001810; F-box.
IPR015915; Kelch-typ_b-propeller.
IPR006652; Kelch_1.
IPR013089; Kelch_related.
Graphical view of domain structure.
Gene3D G3DSA:2.120.10.80; Kelch-typ_b-propeller; 1.
PANTHER PTHR23230; Kelch_related; 1.
Pfam PF00646; F-box; 1.
PF01344; Kelch_1; 2.
Pfam graphical view of domain structure.
SMART SM00256; FBOX; 1.
SM00612; Kelch; 2.
SMART graphical view of domain structure.
PROSITE PS50181; FBOX; FALSE_NEG.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q8LAW2.
Genome annotation databases
GeneID 816990; -.
GenomeReviews CT485783_GR; AT2G24540.
KEGG ath:AT2G24540; -.
NMPDR fig|3702.1.peg.9478; -.
Other
ProtoNet Q8LAW2.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Kelch repeat; Phytochrome signaling pathway; Repeat; Ubl conjugation pathway.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   372  372     Protein AFR. PRO_0000119959
DOMAIN   29    74  46     F-box. 
REPEAT   80   126  47     Kelch 1. 
REPEAT   135   178  44     Kelch 2. 
REPEAT   179   227  49     Kelch 3. 
REPEAT   229   276  48     Kelch 4. 
REPEAT   279   325  47     Kelch 5. 
CONFLICT   130   130        M -> I (in Ref. 3; AAM65112). 
CONFLICT   246   246        Q -> E (in Ref. 3; AAM65112). 
CONFLICT   307   307        Q -> P (in Ref. 3; AAM65112). 
CONFLICT   351   351        R -> K (in Ref. 3; AAM65112). 
Sequence information
Length: 372 AA [This is the length of the unprocessed precursor] Molecular weight: 41278 Da [This is the MW of the unprocessed precursor] CRC64: 0F48D9747B900634 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAEQETTSNI NTINDQAEEE TRTKSQPLIS GLPNDIAELC LLRLPYPYHA LYRSVSSSWN 

        70         80         90        100        110        120 
KTITNPRFLF SKQSLSISSP YLFVFAFNKS TARIQWQSLD LASGRWFVLP PMPNSFTKIS 

       130        140        150        160        170        180 
SPHALSCASM PRQGKLFVLG GGDVNRSAVV YTALTNRWSC ISPMMSPRTY FVSGNVNGKI 

       190        200        210        220        230        240 
MAVGGSVGGN GEATTEVESY DPDNDTWTVV KKLPMVLAKY DSAVIGKEMC VTEGWAWPFM 

       250        260        270        280        290        300 
FPPMGQVYDS DEGTWREMSG GMKEGWTGVS VVIRDRLFVI SEHGDFPMKV YCSDDDTWRY 

       310        320        330        340        350        360 
VSGEKLQGEK MRRPFAVTGA DDRVFVVASG INVAEGRVSE GQNGDFSVEW RMVSSPKSSI 

       370 
QFSPASCHVL YV 

Q8LAW2 in FASTA format

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