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UniProtKB/Swiss-Prot entry Q8L7U5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name BSL1_ARATH
Primary accession number Q8L7U5
Secondary accession number Q9ZTA4
Integrated into Swiss-Prot on March 15, 2004
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 47)
Name and origin of the protein
Protein name Serine/threonine-protein phosphatase BSL1
Synonyms EC 3.1.3.16
BSU1-like protein 1
Gene name
Name: BSL1
OrderedLocusNames: At4g03080
ORFNames: T4I9.4
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/47134; PubMed=10617198 [NCBI, ExPASy, EBI, Israel, Japan]
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.;
"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
Nature 402:769-777(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
FUNCTION, AND TISSUE SPECIFICITY.
DOI=10.1101/gad.1174204; PubMed=14977918 [NCBI, ExPASy, EBI, Israel, Japan]
Mora-Garcia S., Vert G., Yin Y., Cano-Delgado A., Cheong H., Chory J.;
"Nuclear protein phosphatases with Kelch-repeat domains modulate the response to brassinosteroids in Arabidopsis.";
Genes Dev. 18:448-460(2004).
[4]
GENE FAMILY, AND NOMENCLATURE.
DOI=10.1016/j.tplants.2007.03.003; PubMed=17368080 [NCBI, ExPASy, EBI, Israel, Japan]
Farkas I., Dombradi V., Miskei M., Szabados L., Koncz C.;
"Arabidopsis PPP family of serine/threonine phosphatases.";
Trends Plant Sci. 12:169-176(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF069442; AAC79097.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL161496; CAB77793.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY126992; AAM83219.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T01385; T01385.
3D structure databases
HSSP P36873; 1IT6. [HSSP ENTRY / PDB]
ModBase Q8L7U5.
Organism-specific databases
TAIR At4g03080; -.
Gene expression databases
ArrayExpress Q8L7U5; -.
GermOnline AT4G03080; Arabidopsis thaliana.
Ontologies
GO
GO:0005634; Cellular component: nucleus (inferred from electronic annotation from UniProtKB-KW).
GO:0005506; Molecular function: iron ion binding (inferred from electronic annotation from InterPro).
GO:0030145; Molecular function: manganese ion binding (inferred from electronic annotation from InterPro).
GO:0004721; Molecular function: phosphoprotein phosphatase activity (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR015915; Kelch-typ_b-propeller.
IPR006652; Kelch_1.
IPR011498; Kelch_2.
IPR004843; M-pesterase.
IPR012391; PPP_BSU1.
IPR006186; T_phtase_apaH.
Graphical view of domain structure.
Gene3D G3DSA:2.120.10.80; Kelch-typ_b-propeller; 2.
PANTHER PTHR11668; T_phtase_apaH; 1.
Pfam PF01344; Kelch_1; 2.
PF07646; Kelch_2; 1.
PF00149; Metallophos; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036363; PPP_BSU1; 1.
PRINTS PR00114; STPHPHTASE.
ProDom PD000252; T_phtase_apaH; 1.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00156; PP2Ac; 1.
SMART graphical view of domain structure.
PROSITE PS00125; SER_THR_PHOSPHATASE; 1.
ProtoNet Q8L7U5.
Proteomic databases
ProMEX Q8L7U5; -.
Genome annotation databases
GenomeReviews CT486007_GR; AT4G03080.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Iron; Kelch repeat; Manganese; Metal-binding; Nucleus; Protein phosphatase; Repeat.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   881  881     Serine/threonine-protein phosphatase BSL1. PRO_0000058905
REPEAT   60   109  50     Kelch 1. 
REPEAT   269   320  52     Kelch 2. 
REPEAT   338   385  48     Kelch 3. 
ACT_SITE   651   651        Proton donor (By similarity). 
METAL   584   584        Iron (By similarity). 
METAL   586   586        Iron (By similarity). 
METAL   618   618        Iron (By similarity). 
METAL   618   618        Manganese (By similarity). 
METAL   650   650        Manganese (By similarity). 
METAL   703   703        Manganese (By similarity). 
METAL   782   782        Manganese (By similarity). 
Sequence information
Length: 881 AA [This is the length of the unprocessed precursor] Molecular weight: 96115 Da [This is the MW of the unprocessed precursor] CRC64: CFC54406BBFAD6E1 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGSKPWLHPA PQYKTLETFW DDEDDAPGPR CAHTLTAVAA TKTHGPRLIL FGGATAIEGG 

        70         80         90        100        110        120 
SSSVPGIRLA GVTNTVHSYD ILTRKWTRLK PAGEPPSPRA AHAAAAVGTM VVFQGGIGPA 

       130        140        150        160        170        180 
GHSTDDLYVL DMTNDKFKWH RVVVQGDGPG PRYGHVMDLV SQRYLVTVTG NDGKRALSDA 

       190        200        210        220        230        240 
WALDTAQKPY VWQRLNPDGD RPSARMYASG SARSDGMFLL CGGRDTLGAP LGDAYGLLMH 

       250        260        270        280        290        300 
RNGQWEWTLA PGVAPSPRYQ HAAVFVGARL HVSGGVLRGG RVIDAEASVA VLDTAAGVWL 

       310        320        330        340        350        360 
DRNGQVTSAR GSKGQIDQDP SFELMRRCRH GAASVGIRIY VHGGLRGDVL LDDFLVAENS 

       370        380        390        400        410        420 
TFQSDISSPL LASDRTQQSS TPRFSYAARP PSGSEPSFSM SEGLSLDENS LEKLTEASAA 

       430        440        450        460        470        480 
EAEVASSVWR AAQLGAGTLD EEPSTSDASS PIVESTTDGT ANEGDVRLHP RAVVVAKETV 

       490        500        510        520        530        540 
GSLGGMVRQL SLDQFQNESR RMVPMNNSDV PQPTKKFTRQ KSPQGLHKKV IAALLRPRNW 

       550        560        570        580        590        600 
KPPGNRKFFL DSYEVGELCY AAEQIFMHEQ TVLQLKAPIK VFGDLHGQFG DLMRLFDEYG 

       610        620        630        640        650        660 
FPSTAGDITY IDYLFLGDYV DRGQHSLETI TLLLALKIEY PENVHLIRGN HEAADINALF 

       670        680        690        700        710        720 
GFRLECIERM GENDGIWAWT RFNQLFNYLP LAALIENKII CMHGGIGRSI STVEQIEKIE 

       730        740        750        760        770        780 
RPITMDAGSL VLMDLLWSDP TENDSIEGLR PNARGPGLVT FGPDRVTEFC KRNKLQLIIR 

       790        800        810        820        830        840 
AHECVMDGFE RFAPGQLITL FSATNYCGTA NNAGAILVVG RGLVIVPKLI HPLPPPILSP 

       850        860        870        880 
ENSPEHSGDD AWMQELNIQR PPTPTRGRPQ PDFDRSSLAY I 

Q8L7U5 in FASTA format

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