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UniProtKB/Swiss-Prot entry Q8L7I0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUN19_ARATH
Primary accession number Q8L7I0
Secondary accession number O82513
Integrated into Swiss-Prot on September 5, 2006
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 41)
Name and origin of the protein
Protein name Endoglucanase 19 [Precursor]
Synonyms EC 3.2.1.4
Endo-1,4-beta glucanase 19
Gene name
OrderedLocusNames: At4g11050
ORFNames: F2P3.1, T22B4.30
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/47134; PubMed=10617198 [NCBI, ExPASy, EBI, Israel, Japan]
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.;
"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
Nature 402:769-777(1999).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[3]
GENE FAMILY.
DOI=10.1007/s00239-003-2571-x; PubMed=15170254 [NCBI, ExPASy, EBI, Israel, Japan]
Libertini E., Li Y., McQueen-Mason S.J.;
"Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family.";
J. Mol. Evol. 58:506-515(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF080120; AAC35539.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL049876; CAB43040.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL161518; CAB81206.1; ALT_SEQ; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY133685; AAM91619.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T01929; T01929.
RefSeq NP_192843.2; -.
UniGene At.33589
3D structure databases
HSSP Q9EYQ2; 1IA6. [HSSP ENTRY / PDB]
ModBase Q8L7I0.
Organism-specific databases
TAIR At4g11050; -.
Gene expression databases
GermOnline AT4G11050; Arabidopsis thaliana.
Ontologies
GO
GO:0005576; Cellular component: extracellular region (inferred from electronic annotation from UniProtKB-KW).
GO:0030246; Molecular function: carbohydrate binding (inferred from electronic annotation from InterPro).
GO:0008810; Molecular function: cellulase activity (inferred from electronic annotation from EC).
GO:0007047; Biological process: cell wall organization (inferred from electronic annotation from UniProtKB-KW).
GO:0030245; Biological process: cellulose catabolic process (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
InterPro IPR012341; 6hp_glycosidase.
IPR001701; Glyco_hydro_9.
Graphical view of domain structure.
Gene3D G3DSA:1.50.10.10; CelA/Cel48F_cat; 1.
PANTHER PTHR22298:SF3; Glyco_hydro_9; 1.
Pfam PF00759; Glyco_hydro_9; 1.
Pfam graphical view of domain structure.
PROSITE PS00592; GLYCOSYL_HYDROL_F9_1; 1.
PS00698; GLYCOSYL_HYDROL_F9_2; 1.
ProtoNet Q8L7I0.
Genome annotation databases
GeneID 826706; -.
GenomeReviews CT486007_GR; AT4G11050.
KEGG ath:AT4G11050; -.
NMPDR fig|3702.1.peg.18770; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Cell wall biogenesis/degradation; Cellulose degradation; Complete proteome; Glycoprotein; Glycosidase; Hydrolase; Polysaccharide degradation; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
SIGNAL   1    23  23     Potential. 
CHAIN   24   626  603     Endoglucanase 19. PRO_0000249271
ACT_SITE   412   412        By similarity. 
ACT_SITE   464   464        By similarity. 
ACT_SITE   473   473        By similarity. 
CARBOHYD   560   560        N-linked (GlcNAc...) (Potential). 
CARBOHYD   622   622        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 626 AA [This is the length of the unprocessed precursor] Molecular weight: 69345 Da [This is the MW of the unprocessed precursor] CRC64: 6F7457C97EEF655F [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGSRTTISIL VVLLLGLVQL AISGHDYKQA LSKSILFFEA QRSGHLPPNQ RVSWRSHSGL 

        70         80         90        100        110        120 
YDGKSSGVDL VGGYYDAGDN VKFGLPMAFT VTTMCWSIIE YGGQLESNGE LGHAIDAVKW 

       130        140        150        160        170        180 
GTDYFIKAHP EPNVLYGEVG DGKSDHYCWQ RPEEMTTDRR AYKIDRNNPG SDLAGETAAA 

       190        200        210        220        230        240 
MAAASIVFRR SDPSYSAELL RHAHQLFEFA DKYRGKYDSS ITVAQKYYRS VSGYNDELLW 

       250        260        270        280        290        300 
AAAWLYQATN DKYYLDYLGK NGDSMGGTGW SMTEFGWDVK YAGVQTLVAK VLMQGKGGEH 

       310        320        330        340        350        360 
TAVFERYQQK AEQFMCSLLG KSTKNIKKTP GGLIFRQSWN NMQFVTSASF LATVYSDYLS 

       370        380        390        400        410        420 
YSKRDLLCSQ GNISPSQLLE FSKSQVDYIL GDNPRATSYM VGYGENYPRQ VHHRGSSIVS 

       430        440        450        460        470        480 
FNVDQKFVTC RGGYATWFSR KGSDPNVLTG ALVGGPDAYD NFADQRDNYE QTEPATYNNA 

       490        500        510        520        530        540 
PLLGVLARLI SGSTGFDQLL PGVSPTPSPV IIKPAPVPQR KPTKPPAASS PSPITISQKM 

       550        560        570        580        590        600 
TNSWKNEGKV YYRYSTILTN RSTKTLKILK ISITKLYGPI WGVTKTGNSF SFPSWMQSLP 

       610        620 
SGKSMEFVYI HSASPADVLV SNYSLE 

Q8L7I0 in FASTA format

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