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UniProtKB/Swiss-Prot entry Q8L1Z5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TPIS_BARHE
Primary accession number Q8L1Z5
Secondary accession numbers None
Integrated into Swiss-Prot on December 15, 2003
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 38)
Name and origin of the protein
Protein name Triosephosphate isomerase
Synonyms TIM
EC 5.3.1.1
Triose-phosphate isomerase
Gene name
Name: tpiA
OrderedLocusNames: BH05680
From
Bartonella henselae (Rochalimaea henselae) [TaxID: 38323] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bartonellaceae; Bartonella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 49882 / Houston 1;
DOI=10.1073/pnas.082112499; PubMed=11983902 [NCBI, ExPASy, EBI, Israel, Japan]
Canback B., Andersson S.G.E., Kurland C.G.;
"The global phylogeny of glycolytic enzymes.";
Proc. Natl. Acad. Sci. U.S.A. 99:6097-6102(2002).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 49882 / Houston 1;
DOI=10.1073/pnas.0305659101; PubMed=15210978 [NCBI, ExPASy, EBI, Israel, Japan]
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.;
"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae.";
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AY074775; AAL74288.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BX897699; CAF27376.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_033402.1; -.
3D structure databases
HSSP P36204; 1B9B. [HSSP ENTRY / PDB]
ModBase Q8L1Z5.
Enzyme and pathway databases
BioCyc BHEN283166:BH05680-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004807; Molecular function: triose-phosphate isomerase activity (inferred from electronic annotation from HAMAP).
GO:0006094; Biological process: gluconeogenesis (inferred from electronic annotation from HAMAP).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
GO:0006098; Biological process: pentose-phosphate shunt (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00147; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR000652; Triophos_ismrse.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
PANTHER PTHR21139; Triophos_ismrse; 1.
Pfam PF00121; TIM; 1.
Pfam graphical view of domain structure.
ProDom PD001005; Triophos_ismrse; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00419; tim; 1.
PROSITE PS00171; TIM; 1.
ProtoNet Q8L1Z5.
Genome annotation databases
GeneID 2865236; -.
GenomeReviews BX897699_GR; BH05680.
KEGG bhe:BH05680; -.
NMPDR fig|283166.1.peg.530; -.
Phylogenomic databases
HOGENOM Q8L1Z5; -.
Genome annotation databases
CMR Q8L1Z5; BH05680.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   254  254     Triosephosphate isomerase. PRO_0000090181
ACT_SITE   99    99        Electrophile (By similarity). 
ACT_SITE   169   169        Proton acceptor (By similarity). 
BINDING   12    12        Substrate (By similarity). 
BINDING   14    14        Substrate (By similarity). 
Sequence information
Length: 254 AA [This is the length of the unprocessed precursor] Molecular weight: 27165 Da [This is the MW of the unprocessed precursor] CRC64: 50BB63614C90769F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSPNIRPFIA GNWKMNGTGE SLGELRAIAA GISSDLGRLF EALICVPATL LSRAFDILGG 

        70         80         90        100        110        120 
ENILLGGQNC HFDDYGPYTG DISAFMLKEA GASHVIIGHS ERRTVYQESD AIVRAKVQAA 

       130        140        150        160        170        180 
WRAGLVALIC VGETLEERKS NKVLDVLTRQ LEGSLPDGAT AENIIIAYEP VWAVGTGNTA 

       190        200        210        220        230        240 
TSADVAEVHA FIHHKMHSRF GDEGAKIRLL YGGSVKPSNA FELLSTAHVN GALIGGASLK 

       250 
AIDFLTICDV YRKL
Q8L1Z5 in FASTA format

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