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UniProtKB/Swiss-Prot entry Q8KFK6


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PUR9_CHLTE
Primary accession number Q8KFK6
Secondary accession numbers None
Integrated into Swiss-Prot on June 20, 2003
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 38)
Name and origin of the protein
Protein name Bifunctional purine biosynthesis protein purH
Synonyms None
Includes Phosphoribosylaminoimidazolecarboxamide formyltransferase
     (EC 2.1.2.3)
     (AICAR transformylase)
IMP cyclohydrolase
     (EC 3.5.4.10)
     (Inosinicase)
     (IMP synthetase)
     (ATIC)
Gene name
Name: purH
OrderedLocusNames: CT0320
From
Chlorobium tepidum [TaxID: 1097] [HAMAP proteome]
Taxonomy Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 49652 / DSM 12025 / TLS;
DOI=10.1073/pnas.132181499; PubMed=12093901 [NCBI, ExPASy, EBI, Israel, Japan]
Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M., Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M.;
"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium.";
Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE006470; AAM71566.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_661224.1; -.
3D structure databases
HSSP P31335; 1G8M. [HSSP ENTRY / PDB]
ModBase Q8KFK6.
Enzyme and pathway databases
BioCyc CTEP194439:CT_0320-MON; -.
Ontologies
GO
GO:0003937; Molecular function: IMP cyclohydrolase activity (inferred from electronic annotation from HAMAP).
GO:0004643; Molecular function: phosphoribosylaminoimidazolecarboxamide formyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006188; Biological process: IMP biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00139; -; 1.
PBIL [Tree]
InterPro IPR002695; AICARFT_IMPCHas.
IPR013982; AICARFT_IMPCHas_formly.
IPR011607; MGS.
Graphical view of domain structure.
PANTHER PTHR11692; AICARFT_IMPCHas; 1.
Pfam PF01808; AICARFT_IMPCHas; 1.
PF02142; MGS; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000414; AICARFT_IMPCHas; 1.
SMART SM00798; AICARFT_IMPCHas; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00355; purH; 1.
ProtoNet Q8KFK6.
Genome annotation databases
GeneID 1007981; -.
GenomeReviews AE006470_GR; CT0320.
KEGG cte:CT0320; -.
NMPDR fig|194439.1.peg.318; -.
TIGR CT0320; -.
Phylogenomic databases
HOGENOM Q8KFK6; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Multifunctional enzyme; Purine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   523  523     Bifunctional purine biosynthesis protein purH. PRO_0000192082
Sequence information
Length: 523 AA [This is the length of the unprocessed precursor] Molecular weight: 56743 Da [This is the MW of the unprocessed precursor] CRC64: EB17A1E65D679920 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLDPVIKRAL VSVSDKTGIV DFCRELASMD VEIFSTGGTL KLLQGAGIVA QSISTITGFP 

        70         80         90        100        110        120 
EIMDGRVKTL HPKIHGGLLA VRDNAEHQKA ARENGIQFID LVVVNLYPFE ATIAKADVTF 

       130        140        150        160        170        180 
EEAIENIDIG GPSMLRSAAK NNESVTVVTD VADYATVLDE MRSNGGATTR ATRLTLAAKV 

       190        200        210        220        230        240 
YALTSRYDTA IAAYMAKAAG VKGAGDTMTL KLEKELSMRY GENPHQSAGL YKMDDGNGVR 

       250        260        270        280        290        300 
SFSAIFEKLH GKELSYNNML DIAAATGIIE EFRGEEPSVV IVKHTNPCGV AQAPTLCEAY 

       310        320        330        340        350        360 
RKAFSTDTQA PFGGIIAFNR PLDMETASAV NEIFTEILIA PAFEDGVLEM LMKKKDRRLV 

       370        380        390        400        410        420 
LQKQPLPKAG WEFKSTPFGM LVQERDSKTV APEELKVVTK RQPTAEELAD LMFAWKIVRH 

       430        440        450        460        470        480 
IKSNTILYVK NRQTFGVGAG QMSRVDSSKI ARWKASEVAL DLRGSVVASD AFFPFADGLL 

       490        500        510        520 
AAAEAGVTAV IQPGGSIRDN EVIEAADANN LAMVFTGMRH FKH 

Q8KFK6 in FASTA format

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