ID   NTPA_CHLTE              Reviewed;         226 AA.
AC   Q8KFJ6;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   22-JUL-2008, entry version 32.
DE   RecName: Full=Nucleoside-triphosphatase;
DE            EC=3.6.1.15;
DE   AltName: Full=Nucleoside triphosphate phosphohydrolase;
DE            Short=NTPase;
GN   OrderedLocusNames=CT0330;
OS   Chlorobium tepidum.
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Chlorobaculum.
OX   NCBI_TaxID=1097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49652 / DSM 12025 / TLS;
RX   MEDLINE=22103685; PubMed=12093901; DOI=10.1073/pnas.132181499;
RA   Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M.,
RA   Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H.,
RA   Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F.,
RA   Holt I.E., Umayam L.A., Mason T.M., Brenner M., Shea T.P.,
RA   Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B.,
RA   Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M.,
RA   Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M.;
RT   "The complete genome sequence of Chlorobium tepidum TLS, a
RT   photosynthetic, anaerobic, green-sulfur bacterium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
CC   -!- FUNCTION: Hydrolyzes non-standard nucleotides such as XTP and
CC       dITP/ITP. Might exclude non-standard purines from DNA precursor
CC       pool, preventing thus incorporation into DNA and avoiding
CC       chromosomal lesions (By similarity).
CC   -!- CATALYTIC ACTIVITY: NTP + H(2)O = NDP + phosphate.
CC   -!- COFACTOR: Divalent cations (By similarity).
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SIMILARITY: Belongs to the HAM1 NTPase family.
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DR   EMBL; AE006470; AAM71576.1; -; Genomic_DNA.
DR   RefSeq; NP_661234.1; -.
DR   HSSP; Q57679; 1B78.
DR   GeneID; 1007992; -.
DR   GenomeReviews; AE006470_GR; CT0330.
DR   KEGG; cte:CT0330; -.
DR   NMPDR; fig|194439.1.peg.328; -.
DR   TIGR; CT0330; -.
DR   HOGENOM; Q8KFJ6; -.
DR   BioCyc; CTEP194439:CT_0330-MON; -.
DR   GO; GO:0017111; F:nucleoside-triphosphatase activity; IEA:HAMAP.
DR   HAMAP; MF_01405; -; 1.
DR   InterPro; IPR002637; Ham1p_like.
DR   PANTHER; PTHR11067; Ham1p_like; 1.
DR   Pfam; PF01725; Ham1p_like; 1.
DR   TIGRFAMs; TIGR00042; Ham1p_like; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    226       Nucleoside-triphosphatase.
FT                                /FTId=PRO_0000178151.
SQ   SEQUENCE   226 AA;  24411 MW;  2F5D995E8A69DC59 CRC64;
     MEPKHPEITI VLATGNKDKV RELKPVLEAL ASGIHVRSLH DLGLDIDVEE TEPTLEGNAR
     LKADAIFELV APRLDWFIAL ADDTGLEVDA LGGAPGVYSA RYAPVPEGVA RTYEDNVRHL
     LSEMRGKSKR TARFRTVIAM KGRLPAANGS AVEIEETTDG HIDGLITTEP KGNGGFGYDP
     VFAPEGMDRT FAQLGIDEKN AISHRGRAVV AAAKRIGEYL SQCGIQ
//