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UniProtKB/Swiss-Prot entry Q8KBH8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name AROE_CHLTE
Primary accession number Q8KBH8
Secondary accession numbers None
Integrated into Swiss-Prot on August 22, 2003
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 42)
Name and origin of the protein
Protein name Shikimate dehydrogenase
Synonym EC 1.1.1.25
Gene name
Name: aroE
OrderedLocusNames: CT1809
From
Chlorobium tepidum [TaxID: 1097] [HAMAP proteome]
Taxonomy Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 49652 / DSM 12025 / TLS;
DOI=10.1073/pnas.132181499; PubMed=12093901 [NCBI, ExPASy, EBI, Israel, Japan]
Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M., Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H., Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F., Holt I.E., Umayam L.A., Mason T.M., Brenner M., Shea T.P., Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B., Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M., Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M.;
"The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium.";
Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE006470; AAM73030.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_662688.1; -.
3D structure databases
HSSP Q58484; 1NVT. [HSSP ENTRY / PDB]
ModBase Q8KBH8.
Enzyme and pathway databases
BioCyc CTEP194439:CT_1809-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0050661; Molecular function: NADP binding (inferred from electronic annotation from InterPro).
GO:0004764; Molecular function: shikimate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
GO:0009073; Biological process: aromatic amino acid family biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.
Family and domain databases
HAMAP MF_00222; -; 1.
PBIL [Tree]
InterPro IPR016040; NAD(P)-bd.
IPR011342; Quinate/shikimate_5-DHase.
IPR013708; Shikimate_DHase-bd_N.
IPR006151; Shikm_DHase/Glu-tRNA_Rdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF01488; Shikimate_DH; 1.
PF08501; Shikimate_dh_N; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00507; aroE; 1.
ProtoNet Q8KBH8.
Genome annotation databases
GeneID 1008183; -.
GenomeReviews AE006470_GR; CT1809.
KEGG cte:CT1809; -.
NMPDR fig|194439.1.peg.1782; -.
TIGR CT1809; -.
Phylogenomic databases
HOGENOM Q8KBH8; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Aromatic amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   295  295     Shikimate dehydrogenase. PRO_0000135999
NP_BIND   132   136  5     NADP (By similarity). 
ACT_SITE   72    72        Proton acceptor (Potential). 
Sequence information
Length: 295 AA [This is the length of the unprocessed precursor] Molecular weight: 31734 Da [This is the MW of the unprocessed precursor] CRC64: B0A86744C10FAEA1 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSNSQSKKIF GLIGKHVDYS WSPLIHNTGF EALGLPCVYT IFNIPSPEMI GDALKGSRAL 

        70         80         90        100        110        120 
GIAGFSVTIP YKKTVVPFLD ELSPEALSIG AVNTIVNDNG RLLGYNTDID GFAAPLLPMA 

       130        140        150        160        170        180 
ESIRNRPVCI FGNGGAALAA VEAFRLRFNP SSVLLVVRDT QKAEDMLEEY AYRDLVTIHA 

       190        200        210        220        230        240 
GREIDQPACS KLIRDCRVLV NATPVGTAGR NDHIHSILPT GHGLLHDGQI VYDMVYNPPE 

       250        260        270        280        290 
TPLLAEARAA GATVIAGIEM LIAQAARAFS IWTGQELPVD LVRKTVLAAI EKSEG
Q8KBH8 in FASTA format

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