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UniProtKB/Swiss-Prot entry Q8K9R0

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LEP_BUCAP
Primary accession number Q8K9R0
Secondary accession numbers None
Integrated into Swiss-Prot on November 8, 2002
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 49)
Name and origin of the protein
Protein name Signal peptidase I
Synonyms SPase I
EC 3.4.21.89
Leader peptidase I
Gene name
Name: lepB
OrderedLocusNames: BUsg_250
From
Buchnera aphidicola subsp. Schizaphis graminum [TaxID: 98794] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1071278; PubMed=12089438 [NCBI, ExPASy, EBI, Israel, Japan]
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
"50 million years of genomic stasis in endosymbiotic bacteria.";
Science 296:2376-2379(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE013218; AAM67809.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_660598.1; -.
3D structure databases
HSSP P00803; 1KN9. [HSSP ENTRY / PDB]
ModBase Q8K9R0.
Protein family/group databases
MEROPS S26.001; -.
Enzyme and pathway databases
BioCyc BAPH198804:BUSG250-MON; -.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from InterPro).
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0008236; Molecular function: serine-type peptidase activity (inferred from electronic annotation from InterPro).
GO:0006508; Biological process: proteolysis (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR000223; Pept_S26A_signal_pept_1.
IPR011056; Peptidase_S24_S26_C.
IPR014037; Peptidase_S26A.
Graphical view of domain structure.
Gene3D G3DSA:2.10.109.10; Pept_S24_S26_C; 1.
PANTHER PTHR12383:SF1; Pept_S26A_signal_pept_1; 1.
PTHR12383; Peptidase_S26A; 1.
Pfam PF00717; Peptidase_S24; 1.
Pfam graphical view of domain structure.
PRINTS PR00727; LEADERPTASE.
TIGRFAMs TIGR02227; sigpep_I_bact; 1.
PROSITE PS00501; SPASE_I_1; 1.
PS00760; SPASE_I_2; 1.
PS00761; SPASE_I_3; 1.
ProtoNet Q8K9R0.
Genome annotation databases
GeneID 1005452; -.
GenomeReviews AE013218_GR; BUsg_250.
KEGG bas:BUsg250; -.
Phylogenomic databases
HOGENOM Q8K9R0; -.
Genome annotation databases
CMR Q8K9R0; BUsg_250.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Hydrolase; Membrane; Protease; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   312  312     Signal peptidase I. PRO_0000109504
TRANSMEM   7    27  21     Potential. 
TOPO_DOM   28    63  36     Cytoplasmic (Potential). 
TRANSMEM   64    84  21     Potential. 
TOPO_DOM   85   312  228     Extracellular (Potential). 
ACT_SITE   88    88        By similarity. 
ACT_SITE   142   142        By similarity. 
Sequence information
Length: 312 AA [This is the length of the unprocessed precursor] Molecular weight: 37103 Da [This is the MW of the unprocessed precursor] CRC64: 63602053A16A0D8B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MRNILTIFLL TSTFFTGILW IIDHILLIKN YFYNKKKTKN NNTILINKVI LENKKCFFRS 

        70         80         90        100        110        120 
LSSLFPTFFI VFIIRSFIYE PFQIPSGSMM PTLLIGDFIL VKKFSYGIKE PITNKTIIKM 

       130        140        150        160        170        180 
NLPQRGDIVV FKHPKNNIDY IKRVVGLPGD KIQYDINRKK IKICINYTNQ KNCENKLFIT 

       190        200        210        220        230        240 
YSKPKLSNFF QKIYLLKSRT NEEEKVYNSI YFKKVEEKIN NLKHNILILD GINSKINDYY 

       250        260        270        280        290        300 
QQKGMPKLIW IVPKNKYFMM GDNRDNSLDS RYWGFVPEEN LLGKATKIWM SFEKKENEWP 

       310 
TGIRIKRIGN IY
Q8K9R0 in FASTA format

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