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UniProtKB/Swiss-Prot entry Q8K9M3

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name KPYK_BUCAP
Primary accession number Q8K9M3
Secondary accession numbers None
Integrated into Swiss-Prot on November 8, 2002
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 41)
Name and origin of the protein
Protein name Pyruvate kinase
Synonyms PK
EC 2.7.1.40
Gene name
Name: pykA
OrderedLocusNames: BUsg_311
From
Buchnera aphidicola subsp. Schizaphis graminum [TaxID: 98794] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1071278; PubMed=12089438 [NCBI, ExPASy, EBI, Israel, Japan]
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
"50 million years of genomic stasis in endosymbiotic bacteria.";
Science 296:2376-2379(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE013218; AAM67865.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_660654.1; -.
3D structure databases
HSSP P14178; 1E0T. [HSSP ENTRY / PDB]
ModBase Q8K9M3.
Enzyme and pathway databases
BioCyc BAPH198804:BUSG311-MON; -.
Ontologies
GO
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from InterPro).
GO:0030955; Molecular function: potassium ion binding (inferred from electronic annotation from InterPro).
GO:0004743; Molecular function: pyruvate kinase activity (inferred from electronic annotation from InterPro).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR001697; Pyr_Knase.
IPR015813; Pyrv/PenolPyrv_Kinase_cat.
IPR015794; Pyrv_Knase_a/b.
IPR015793; Pyrv_Knase_brl.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.60; Pyrv/PenolPyrv_Kinase_cat; 1.
G3DSA:3.40.1380.20; Pyrv_Knase_a/b; 1.
PANTHER PTHR11817; Pyruvate_kinase; 1.
Pfam PF00224; PK; 1.
PF02887; PK_C; 1.
Pfam graphical view of domain structure.
PRINTS PR01050; PYRUVTKNASE.
ProDom PD001009; Pyruvate_kinase; 2.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR01064; pyruv_kin; 1.
PROSITE PS00110; PYRUVATE_KINASE; 1.
ProtoNet Q8K9M3.
Genome annotation databases
GeneID 1005515; -.
GenomeReviews AE013218_GR; BUsg_311.
KEGG bas:BUsg311; -.
Phylogenomic databases
HOGENOM Q8K9M3; -.
Genome annotation databases
CMR Q8K9M3; BUsg_311.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glycolysis; Kinase; Magnesium; Metal-binding; Pyruvate; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   481  481     Pyruvate kinase. PRO_0000112059
ACT_SITE   223   223        By similarity. 
METAL   225   225        Magnesium (By similarity). 
METAL   249   249        Magnesium (By similarity). 
METAL   250   250        Magnesium (By similarity). 
Sequence information
Length: 481 AA [This is the length of the unprocessed precursor] Molecular weight: 52632 Da [This is the MW of the unprocessed precursor] CRC64: 8A11ECA79EAB8A3B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLNRVRRTKI VATLGPSTDK ANNLEKIILS GANVLRLNFS HGSSEEHKKR AKKAKEIMFK 

        70         80         90        100        110        120 
LNCHIALLGD LQGPKIRISK FKKNSIFLKV NDVFILDANL NEKNGNNERV GIDYKKLPND 

       130        140        150        160        170        180 
LNVNDILLLD DGRIQLKVIK IEKCAIFTKV IIGGILSNNK GINKLGGGLS ADALTEKDKK 

       190        200        210        220        230        240 
DIILASEIDV DYLAVSFPRC ADDLIKAREL LKKSGSNAQI IAKIERAEAV FDQNAIENII 

       250        260        270        280        290        300 
LSSDAIMIAR GDLGVEIGDA ELVGIQKKLI RTARKLNKVA ITATQMMESM ILNPLPTRAE 

       310        320        330        340        350        360 
VMDVANAVLD GSDAVMLSAE TASGKYPSET VISMAKVCKG AEKVPSINVS RHRLNVEFQS 

       370        380        390        400        410        420 
IEEAIAMSSM YAANHLKGIT AIITMTESGK TALMTSRITS GLPIFALSKH KKTLNLTALY 

       430        440        450        460        470        480 
RGVIPIYFDS DKDGVEAANE AIILLCKKKF LFNNDLVIVT QGDIMGKIGK TNTSRILRVT 


Y
Q8K9M3 in FASTA format

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