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UniProtKB/Swiss-Prot entry Q8K9H5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PNP_BUCAP
Primary accession number Q8K9H5
Secondary accession numbers None
Integrated into Swiss-Prot on November 15, 2002
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 47)
Name and origin of the protein
Protein name Polyribonucleotide nucleotidyltransferase
Synonyms EC 2.7.7.8
Polynucleotide phosphorylase
PNPase
Gene name
Name: pnp
OrderedLocusNames: BUsg_361
From
Buchnera aphidicola subsp. Schizaphis graminum [TaxID: 98794] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1126/science.1071278; PubMed=12089438 [NCBI, ExPASy, EBI, Israel, Japan]
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.;
"50 million years of genomic stasis in endosymbiotic bacteria.";
Science 296:2376-2379(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE013218; AAM67914.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_660703.1; -.
3D structure databases
HSSP P05055; 1SRO. [HSSP ENTRY / PDB]
SMR Q8K9H5; 617-691.
ModBase Q8K9H5.
Enzyme and pathway databases
BioCyc BAPH198804:BUSG361-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0000175; Molecular function: 3'-5'-exoribonuclease activity (inferred from electronic annotation from InterPro).
GO:0004654; Molecular function: polyribonucleotide nucleotidyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0003723; Molecular function: RNA binding (inferred from electronic annotation from InterPro).
GO:0006402; Biological process: mRNA catabolic process (inferred from electronic annotation from HAMAP).
GO:0006396; Biological process: RNA processing (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_01595; -; 1.
PBIL [Tree]
InterPro IPR001247; ExoRNase_PH_dom1.
IPR015847; ExoRNase_PH_dom2.
IPR004087; KH.
IPR004088; KH_type_1.
IPR012340; NA-bd_OB-fold.
IPR012162; PNPase.
IPR015848; PNPase_PH_RNA-bd_bac/org-type.
IPR003029; S1_RNA-bd.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
G3DSA:1.10.10.400; PNPase_PH_RNA-bd_bac/org-type; 1.
PANTHER PTHR11252; PNPase; 1.
Pfam PF00013; KH_1; 1.
PF03726; PNPase; 1.
PF01138; RNase_PH; 2.
PF03725; RNase_PH_C; 2.
PF00575; S1; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF005499; PNPase; 1.
SMART SM00322; KH; 1.
SM00316; S1; 1.
SMART graphical view of domain structure.
PROSITE PS50084; KH_TYPE_1; 1.
PS50126; S1; 1.
PROSITE graphical view of domain structure (profiles).
ProtoNet Q8K9H5.
Genome annotation databases
GeneID 1005794; -.
GenomeReviews AE013218_GR; BUsg_361.
KEGG bas:BUsg361; -.
Phylogenomic databases
HOGENOM Q8K9H5; -.
Genome annotation databases
CMR Q8K9H5; BUsg_361.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Nucleotidyltransferase; RNA-binding; Transferase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   707  707     Polyribonucleotide nucleotidyltransferase. PRO_0000197911
DOMAIN   553   612  60     KH. 
DOMAIN   622   690  69     S1 motif. 
Sequence information
Length: 707 AA [This is the length of the unprocessed precursor] Molecular weight: 78389 Da [This is the MW of the unprocessed precursor] CRC64: 9D5367E96E91520A [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLNPIVRKFQ YGQHTITLET GIMARQATAA VMASMDDTAV FVTVVGEKTT NSSQKFFPLT 

        70         80         90        100        110        120 
VNYQERTYAV GRIPGGFFRR EGRPSENEIL TARLIDRPIR PLFPKGFCNE IQIIATVVSV 

       130        140        150        160        170        180 
NPQINPDIIS IIGASAALSL SGIPFYGPIG AARVGFVNNQ YVLNPTIDDM KSSFLDLVVS 

       190        200        210        220        230        240 
GTQNAVLMVE AESKVLSEDK ILGAIMFGHQ QQQVVINNIR SLSNEASKLP WIISYPEINT 

       250        260        270        280        290        300 
ELELKITKLA EKDISNAYLI FNKQERYEKL NFLKEEIIKL FFSENSNIDI SEIEDIFEKI 

       310        320        330        340        350        360 
EKNIVRKRIL NNENRIDGRE KDMIRALDIR TGVLPRTHGS SLFTRGETQS LVSVTLGTSR 

       370        380        390        400        410        420 
DAQNLDELLG DKTDNFLFHY NFPPYSVGEI GIVGSPKRRE IGHGRLAKRS LLAVMPKLDD 

       430        440        450        460        470        480 
FPYTIRIVSE ITESNGSSSM ASVCGASLAL MDAGVPIKSA VAGISMGLVK EGDKYVLLSD 

       490        500        510        520        530        540 
ILGDEDHLGD MDFKVSGTEE GITALQMDIK IEGITNEIMR IALNKAKSAR LHILNVMKQA 

       550        560        570        580        590        600 
LSKPRNEISE FAPRIHKIKI NPEKIKDVIG KGGSVIRMLT EETGTIIEIE DDGTIKISAT 

       610        620        630        640        650        660 
IGEKAKNAIR RIEEITAEIE VGRIYSGKVT RIVDFGAFIS IGIGKEGLVH ISQISNKRVE 

       670        680        690        700 
KVSDHLTVDQ IISVKVLEID RQGRLRLSIK EVENSIISNK SINNIYI
Q8K9H5 in FASTA format

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