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UniProtKB/Swiss-Prot entry Q8K5G4


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name HASC1_STRP3
Primary accession number Q8K5G4
Secondary accession number Q79VY2
Integrated into Swiss-Prot on August 30, 2005
Sequence was last modified on October 1, 2002 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 34)
Name and origin of the protein
Protein name UTP--glucose-1-phosphate uridylyltransferase 1
Synonyms EC 2.7.7.9
UDP-glucose pyrophosphorylase 1
UDPGP 1
Alpha-D-glucosyl-1-phosphate uridylyltransferase 1
Uridine diphosphoglucose pyrophosphorylase 1
Gene name
Name: hasC1
Synonyms: hasC
OrderedLocusNames: SpyM3_1853, SPs1849
From
Streptococcus pyogenes serotype M3 [TaxID: 301448] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Streptococcaceae; Streptococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-595 / MGAS315 / Serotype M3;
DOI=10.1073/pnas.152298499; PubMed=12122206 [NCBI, ExPASy, EBI, Israel, Japan]
Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D., Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S., Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.;
"Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence.";
Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=SSI-1 / Serotype M3;
DOI=10.1101/gr.1096703; PubMed=12799345 [NCBI, ExPASy, EBI, Israel, Japan]
Nakagawa I., Kurokawa K., Yamashita A., Nakata M., Tomiyasu Y., Okahashi N., Kawabata S., Yamazaki K., Shiba T., Yasunaga T., Hayashi H., Hattori M., Hamada S.;
"Genome sequence of an M3 strain of Streptococcus pyogenes reveals a large-scale genomic rearrangement in invasive strains and new insights into phage evolution.";
Genome Res. 13:1042-1055(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE014074; AAM80460.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BA000034; BAC64944.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_665657.1; -.
NP_803111.1; -.
3D structure databases
ModBase Q8K5G4.
Enzyme and pathway databases
BioCyc SPYO193567:SPS1849-MON; -.
SPYO198466:SPYM3_1853-MON; -.
Ontologies
GO
GO:0003983; Molecular function: UTP:glucose-1-phosphate uridylyltransferase activity (inferred from electronic annotation from InterPro).
GO:0009058; Biological process: biosynthetic process (inferred from electronic annotation from InterPro).
GO:0006011; Biological process: UDP-glucose metabolic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR005771; GalU_trans_bac.
IPR005835; NTP_transferase.
Graphical view of domain structure.
Pfam PF00483; NTP_transferase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01099; galU; 1.
ProtoNet Q8K5G4.
Genome annotation databases
GeneID 1010168; -.
1066096; -.
GenomeReviews BA000034_GR; SPs1849.
AE014074_GR; SpyM3_1853.
KEGG spg:SpyM3_1853; -.
sps:SPs1849; -.
Phylogenomic databases
HOGENOM Q8K5G4; -.
Genome annotation databases
CMR Q8K5G4; SpyM3_1853.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   304  304     UTP--glucose-1-phosphate uridylyltransferase 1. PRO_0000201369
Sequence information
Length: 304 AA [This is the length of the unprocessed precursor] Molecular weight: 33706 Da [This is the MW of the unprocessed precursor] CRC64: 5D717DF01DBC4411 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTKVRKAIIP AAGLGTRFLP ATKALAKEML PIVDKPTIQF IVEEALKSGI EEILVVTGKA 

        70         80         90        100        110        120 
KRSIEDHFDS NFELEYNLQA KGKNELLKLV DETTAINLHF IRQSHPRGLG DAVLQAKAFV 

       130        140        150        160        170        180 
GNEPFVVMLG DDLMDITNAS AKPLTKQLME DYDKTHASTI AVMKVPHEDV SSYGVIAPQG 

       190        200        210        220        230        240 
KAVKGLYSVD TFVEKPQPED APSDLAIIGR YLLTPEIFDI LERQVPGAGN EVQLTDAIDT 

       250        260        270        280        290        300 
LNKTQRVFAR EFKGNRYDVG DKFGFMKTSI DYALEHPQVK EDLKNYIIKL GKALEKSKVP 


THSK 

Q8K5G4 in FASTA format

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