NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=C57BL/6J;
DOI=10.1093/hmg/11.16.1879; PubMed=12140190 [NCBI, ExPASy, EBI, Israel, Japan]
Kameya S., Hawes N.L., Chang B., Heckenlively J.R., Naggert J.K., Nishina P.M.;
"Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6.";
Hum. Mol. Genet. 11:1879-1886(2002).

Comments

SUBCELLULAR LOCATION: Secreted (Probable).
SIMILARITY: Contains 1 C1q domain.
SIMILARITY: Contains 1 collagen-like domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF469650; AAM89217.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_001035721.1; -.
NP_001035722.1; -.
NP_663588.2; -.

UniGene

Mm.227110

3D structure databases

HSSP

Q03692; 1GR3. [HSSP ENTRY / PDB]

ModBase

Q8K479.

Organism-specific databases

MGI

MGI:2385958; C1qtnf5.

Ontologies

GO:0005576;	Cellular component: extracellular region (inferred from electronic annotation from UniProtKB-KW).
GO:0007601;	Biological process: visual perception (inferred from mutant phenotype from MGI).
QuickGo view.

Family and domain databases

InterPro

IPR001073; C1q.
IPR008160; Collagen.
IPR008983; Tumour_necrosis_fac-like.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.120.40; Tumour_necrosis_fac-like; 1.

Pfam

PF00386; C1q; 1.
PF01391; Collagen; 1.
Pfam graphical view of domain structure.

PRINTS

PR00007; COMPLEMNTC1Q.

SMART

SM00110; C1Q; 1.
SMART graphical view of domain structure.

PROSITE

PS50871; C1Q; 1.
PROSITE graphical view of domain structure (profiles).

ProtoNet

Q8K479.

Genome annotation databases

Ensembl

ENSMUSG00000079592; Mus musculus. [Contig view]

GeneID

235312; -.

KEGG

mmu:235312; -.

Phylogenomic databases

HOVERGEN

Q8K479; -.

Other

NextBio

382581; -.

SOURCE

C1qtnf5; Mus musculus.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Collagen; Secreted; Signal.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`SIGNAL`	`1 15`	`15`	`By similarity.`
`CHAIN`	`16 243`	`228`	`Complement C1q tumor necrosis factor-related protein 5.`	`PRO_0000003536`
`DOMAIN`	`30 95`	`66`	`Collagen-like.`
`DOMAIN`	`99 243`	`145`	`C1q.`

Sequence information

Length: 243 AA [This is the length of the unprocessed precursor]

Molecular weight: 25437 Da [This is the MW of the unprocessed precursor]

CRC64: 9F4D5804349791D9 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MRPLLALLLL GLVSGSPPLD DNKIPSLCPG QPGLPGTPGH HGSQGLPGRD GRDGRDGAPG 

        70         80         90        100        110        120 
APGEKGEGGR PGLPGPRGEP GPRGEAGPMG AIGPAGECSV PPRSAFSAKR SESRVPPPAD 

       130        140        150        160        170        180 
TPLPFDRVLL NEQGHYDPTT GKFTCQVPGV YYFAVHATVY RASLQFDLVK NGQSIASFFQ 

       190        200        210        220        230        240 
YFGGWPKPAS LSGGAMVRLE PEDQVWVQVG VGDYIGIYAS IKTDSTFSGF LVYSDWHSSP 


VFA

Q8K479 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools