NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=USDA 110;
DOI=10.1093/dnares/9.6.189; PubMed=12597275 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110.";
DNA Res. 9:189-197(2002).

Comments

CATALYTIC ACTIVITY: ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.
PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme A from pantothenate: step 1/5 .
SUBCELLULAR LOCATION: Cytoplasm (Probable).
SIMILARITY: Belongs to the prokaryotic pantothenate kinase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000040; BAC45921.1; ALT_INIT; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_767296.1; -.

3D structure databases

HSSP

P15044; 1ESM. [HSSP ENTRY / PDB]

ModBase

Q89WM2.

Enzyme and pathway databases

BioCyc

BJAP224911:BLR0656-MON; -.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0005524;	Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004594;	Molecular function: pantothenate kinase activity (inferred from electronic annotation from HAMAP).
GO:0015937;	Biological process: coenzyme A biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00215; -; 1.
PBIL [Tree]

InterPro

IPR004566; PanK_bact.
IPR006083; PRK_URK.
Graphical view of domain structure.

PANTHER

PTHR10285:SF7; PanK_bact; 1.

Pfam

PF00485; PRK; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000545; Pantothenate_kin; 1.

TIGRFAMs

TIGR00554; panK_bact; 1.

Genome annotation databases

GeneID

1049340; -.

GenomeReviews

BA000040_GR; blr0656.

KEGG

bja:blr0656; -.

NMPDR

fig|224911.1.peg.656; -.

Phylogenomic databases

HOGENOM

Q89WM2; -.

Genome annotation databases

CMR

Q89WM2; blr0656.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 318`	`318`	`Pantothenate kinase.`	`PRO_0000194420`
`NP_BIND`	`96 103`	`8`	`ATP (Potential).`

Sequence information

Length: 318 AA [This is the length of the unprocessed precursor]

Molecular weight: 36712 Da [This is the MW of the unprocessed precursor]

CRC64: 07FB31D15C5471C1 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MDIRAPEQQY NPYRVYTREQ WARLRDDTPM TLEPGEFDRL RSLHDRLDLQ EVEDIYLPLS 

        70         80         90        100        110        120 
RLLSIYVDAM QRLYYAERQF LNIRDRKMPY IIGVAGSVAV GKSTTARVLQ ALLARWSPRP 

       130        140        150        160        170        180 
KVDLITTDGF LYPNAVLDRQ GIMQKKGFPE SYDLPLLLGF LSDIKAGRRH VRAPVYSHLT 

       190        200        210        220        230        240 
YDIVPNQWVE IDQPDILIVE GVNVLQTGKL PRDGKAVPVV SDFFDFSVYI DADEAALRRW 

       250        260        270        280        290        300 
YIKRFLALRD TAFTNPKSYF NRYALLSDEE ATATAIAIWE RTNLANLEDN ILPTRPRATL 

       310 
ILKKGPDHVV ESVALRRL

Q89WM2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools