NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=USDA 110;
DOI=10.1093/dnares/9.6.189; PubMed=12597275 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110.";
DNA Res. 9:189-197(2002).

Comments

CATALYTIC ACTIVITY: ATP + L-homoserine = ADP + O-phospho-L-homoserine.
PATHWAY: Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5 .
SIMILARITY: Belongs to the pseudomonas-type thrB family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000040; BAC46580.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_767955.1; -.

3D structure databases

ModBase

Q89UU4.

Enzyme and pathway databases

BioCyc

BJAP224911:BLR1315-MON; -.

Ontologies

GO:0004413;	Molecular function: homoserine kinase activity (inferred from electronic annotation from HAMAP).
GO:0009088;	Biological process: threonine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00301; -; 1.
PBIL [Tree]

InterPro

IPR002575; APH_trans.
IPR005280; HomSer_Kin_ThrB.
Graphical view of domain structure.

Pfam

PF01636; APH; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR00938; thrB_alt; 1.

Genome annotation databases

GeneID

1049260; -.

GenomeReviews

BA000040_GR; blr1315.

KEGG

bja:blr1315; -.

NMPDR

fig|224911.1.peg.1315; -.

Phylogenomic databases

HOGENOM

Q89UU4; -.

Genome annotation databases

CMR

Q89UU4; blr1315.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Complete proteome; Kinase; Threonine biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 327`	`327`		`Homoserine kinase.`	`PRO_0000172185`

Sequence information

Length: 327 AA [This is the length of the unprocessed precursor]

Molecular weight: 35819 Da [This is the MW of the unprocessed precursor]

CRC64: E141F9F97F66CF79 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAVYTDVAAD ELADFLSQYD LGELLSYKGI AEGVENSNFL LHTTKGSFIL TLYEKRVAKN 

        70         80         90        100        110        120 
DLPFFLALMT HLAEHGVNCP LPVKGRDGEA LRELSGRPAA IITFLEGVWP RKPNAAHCAG 

       130        140        150        160        170        180 
VGEGLARMHL AGANFAIRRA NALSVAGWRP LFDAAASRAD EVQPGLRAFL AAELDYLASG 

       190        200        210        220        230        240 
VWPTNLPEGV IHADLFNDNV FFLGDKLSGI IDFTFACNDM LAYDVAICLN AWCFEPDHSF 

       250        260        270        280        290        300 
NVTKARAFLN AYGRVRKLSE AEEAALPLLA RGAAIRFLLT RLVDWLNVPP GALVRPKDPL 

       310        320 
EYVRKLRFHQ SVSSVRDYGL MPSGLVA

Q89UU4 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools