ID   DNAE2_BRAJA             Reviewed;        1151 AA.
AC   Q89QU8;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-NOV-2008, entry version 40.
DE   RecName: Full=Error-prone DNA polymerase;
DE            EC=2.7.7.7;
GN   Name=dnaE2; OrderedLocusNames=blr3026;
OS   Bradyrhizobium japonicum.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=375;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USDA 110;
RX   MEDLINE=22484998; PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T.,
RA   Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K.,
RA   Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M.,
RA   Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: DNA polymerase involved in damage-induced mutagenesis
CC       and translesion synthesis (TLS). It is not the major replicative
CC       DNA polymerase (By similarity).
CC   -!- CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) =
CC       diphosphate + DNA(n+1).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (Probable).
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-C family. DnaE2
CC       subfamily.
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DR   EMBL; BA000040; BAC48291.1; -; Genomic_DNA.
DR   RefSeq; NP_769666.1; -.
DR   GeneID; 1053315; -.
DR   GenomeReviews; BA000040_GR; blr3026.
DR   KEGG; bja:blr3026; -.
DR   NMPDR; fig|224911.1.peg.3026; -.
DR   HOGENOM; Q89QU8; -.
DR   BioCyc; BJAP224911:BLR3026-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:HAMAP.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:HAMAP.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   GO; GO:0045020; P:error-prone DNA repair; IEA:HAMAP.
DR   HAMAP; MF_01902; -; 1.
DR   InterPro; IPR011708; DNA_pol3_alpha.
DR   InterPro; IPR004365; NA_bd_OB_tRNA-helicase.
DR   InterPro; IPR004013; PHP_C.
DR   InterPro; IPR003141; PHP_N.
DR   InterPro; IPR004805; PolC_alpha.
DR   Pfam; PF07733; DNA_pol3_alpha; 1.
DR   Pfam; PF02811; PHP; 1.
DR   Pfam; PF01336; tRNA_anti; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   TIGRFAMs; TIGR00594; polc; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication;
KW   DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.
FT   CHAIN         1   1151       Error-prone DNA polymerase.
FT                                /FTId=PRO_0000103369.
SQ   SEQUENCE   1151 AA;  129582 MW;  2F0563C7FC4625A7 CRC64;
     MNTPAYAEIG ITTNFSFLRG GSDPRAYVHQ ASILGISAIG IADHNTLAGV VRAYKELDND
     KVLHKPKLLI GARIVFIDGT PDILVYPRDR AAYGRLCQLL TRGKRGDDVT RIEKGECRLT
     FSDLLAFSEG QLLVLTLPHR FEPAQALDVL AKLKATRAEG VWLAASLVHR GDDRRRLARL
     DDLATTAKVQ LLATNEVLYH DPARRPLQDV LTCIREKTTI EAVGRKLEAN AERFLKTPRE
     MSRLFRDFPD AIAETMRFAN KIDFSLDQLR YQYPDEPVPP GKTAQGHLED LTWAGVDKYF
     AGKIDDKLRA TLKKELALIA ELKYAHYFLT VHDIVHYARS QNILCQGRGS AANSAVCYVL
     GITSVDPTKV DLLFERFISK ERLEPPDIDV DFEHSRREEV MQYVYRRYGR HRAAIIATII
     HYRPRSAIRD VGKALGLTED VTAALADTVW GSWGSGLNDM QVKQAGLDPQ NPMINLAVEL
     ATELIEFPRH LSQHVGGYVL TQDRLDTYVP IGNAAMDDRT FIEWDKDDVD ALNMMKVDVL
     ALGMLTCIRK CFDLIDQHKG ERWVLASVPQ DDPKVYDMLC DGESLGVFQV ESRAQMNMLP
     RLKPRTFYDL VIEVAIVRPG PIQGDMVHPY LRRRNGQEKV NYPSPSPEHG PADELYKVLH
     KTKGVPLFQE QAMRIAIEAA KFTSEEANGL RRSMATFRNV GTIGKYEDKL IGNMVARGYD
     PNFARSCFDQ IKGFGSYGFP ESHAASFAQL VYISSWLKYH HPDAFCCGLL NSQPMGFYAP
     AQIVGDARKN GVEVRDIDVS YSFAQNTLEQ GSGKYCAVRL GFRQIDGFHW LDEDEEHLKR
     SLLSFRGAPL GANPESIGPH MPGGMDSGLD AGASPRNDKK EDWANRIVAA RNRRPFTSLE
     DFARDTGLPK RALILLADAD AFRSLGLDRR EALWQVRRLP DDVPLPLFEA ATAREQPDEH
     AKPLPLMPRP EQVVADYQTI RLSLKGHPME FLREMLSRER VVACKDVNHQ NERRRVRCAG
     VVLVRQRPGS ASGVVFMTLE DETGIANVVV WPKIMEQYRK EVMGARLILV EGYIQSSPEK
     VTHLIAQRMV DRSHDLIGLA NDSLTRKHPV PSGDALIEPL NDDRRDHADA PAQKIRHPRN
     VRILPPSRDF H
//