NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=USDA 110;
DOI=10.1093/dnares/9.6.189; PubMed=12597275 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110.";
DNA Res. 9:189-197(2002).

Comments

CATALYTIC ACTIVITY: Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.
PATHWAY: Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from HCO(3)(-): step 2/6 .
SIMILARITY: Belongs to the ATCase/OTCase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000040; BAC50364.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_771739.1; -.

3D structure databases

ModBase

Q89K19.

Enzyme and pathway databases

BioCyc

BJAP224911:BLR5099-MON; -.

Ontologies

GO:0004070;	Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221;	Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00001; -; 1.
PBIL [Tree]

InterPro

IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.

Pfam

PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.

PRINTS

PR00100; AOTCASE.
PR00101; ATCASE.

TIGRFAMs

TIGR00670; asp_carb_tr; 1.

PROSITE

PS00097; CARBAMOYLTRANSFERASE; 1.

BLOCKS

Q89K19.

Genome annotation databases

GeneID

1051765; -.

GenomeReviews

BA000040_GR; blr5099.

KEGG

bja:blr5099; -.

NMPDR

fig|224911.1.peg.5099; -.

Phylogenomic databases

HOGENOM

Q89K19; -.

Genome annotation databases

CMR

Q89K19; blr5099.

Other

ProtoNet

Q89K19.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Pyrimidine biosynthesis; Transferase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 315`	`315`		`Aspartate carbamoyltransferase.`	`PRO_0000113107`

Sequence information

Length: 315 AA [This is the length of the unprocessed precursor]

Molecular weight: 34201 Da [This is the MW of the unprocessed precursor]

CRC64: CA7975402C637239 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MTSKSTFVLG HRHLLGIEGL SAADITGLLD LSEEYVELNR QVDKKRTVLR GRTQVNLFFE 

        70         80         90        100        110        120 
ASTRTQSSFE LAGKRLGADV MNMSVSSSSI KKGETLVDTA MTLNAMHPDI LVVRHHASGA 

       130        140        150        160        170        180 
VELLARKVDG SVINAGDGAH EHPTQALLDA LTIRRNKGRI EGLVVAICGD VLHSRVARSN 

       190        200        210        220        230        240 
IILLNTMGAR VRVVGPSTLL PPGIERMGVE VARDMREGLN GADIVMMLRL QRERMNGSFV 

       250        260        270        280        290        300 
PSTSEYFNYF GLDQKKLGYA KPDALVMHPG PMNRGVEIDT AVADGAQSLI REQVEMGVAV 

       310 
RMAVLEALAR NLPNA

Q89K19 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools