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UniProtKB/Swiss-Prot entry Q89HP6

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name SAHH_BRAJA
Primary accession number Q89HP6
Secondary accession numbers None
Integrated into Swiss-Prot on June 20, 2003
Sequence was last modified on June 20, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 38)
Name and origin of the protein
Protein name Adenosylhomocysteinase
Synonyms EC 3.3.1.1
S-adenosyl-L-homocysteine hydrolase
AdoHcyase
Gene name
Name: ahcY
OrderedLocusNames: bll5944
From
Bradyrhizobium japonicum [TaxID: 375] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales; Bradyrhizobiaceae; Bradyrhizobium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=USDA 110;
DOI=10.1093/dnares/9.6.189; PubMed=12597275 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110.";
DNA Res. 9:189-197(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000040; BAC51209.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_772584.1; -.
3D structure databases
HSSP P10760; 1B3R. [HSSP ENTRY / PDB]
ModBase Q89HP6.
Enzyme and pathway databases
BioCyc BJAP224911:BLL5944-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004013; Molecular function: adenosylhomocysteinase activity (inferred from electronic annotation from HAMAP).
GO:0005488; Molecular function: binding (inferred from electronic annotation from InterPro).
GO:0006730; Biological process: one-carbon compound metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00563; -; 1.
PBIL [Tree]
InterPro IPR000043; Ad_hcy_hydrolase.
IPR015878; Ado_hCys_hydrolase_NAD-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.1480; Ad_hcy_hydrolase; 1.
PANTHER PTHR23420; Ad_hcy_hydrolase; 1.
Pfam PF05221; AdoHcyase; 1.
PF00670; AdoHcyase_NAD; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF001109; Ad_hcy_hydrolase; 1.
TIGRFAMs TIGR00936; ahcY; 1.
PROSITE PS00738; ADOHCYASE_1; 1.
PS00739; ADOHCYASE_2; 1.
BLOCKS Q89HP6.
ProtoNet Q89HP6.
Genome annotation databases
GeneID 1054354; -.
GenomeReviews BA000040_GR; bll5944.
KEGG bja:bll5944; -.
NMPDR fig|224911.1.peg.5944; -.
Phylogenomic databases
HOGENOM Q89HP6; -.
Genome annotation databases
CMR Q89HP6; bll5944.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Hydrolase; NAD; One-carbon metabolism.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   473  473     Adenosylhomocysteinase. PRO_0000116950
REGION   224   389  166     NAD binding (By similarity). 
BINDING   60    60        Substrate (By similarity). 
BINDING   135   135        Substrate (By similarity). 
BINDING   197   197        Substrate (By similarity). 
BINDING   227   227        Substrate (By similarity). 
BINDING   231   231        Substrate (By similarity). 
Sequence information
Length: 473 AA [This is the length of the unprocessed precursor] Molecular weight: 52066 Da [This is the MW of the unprocessed precursor] CRC64: 363C0EBECD03B502 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MNAKPGFTDY IVKDISLADF GRKELSLAET EMPGLMATRE EFGPKQPLKG ARIAGSLHMT 

        70         80         90        100        110        120 
IQTGVLIETL AALGADIRWV SCNIYSTQDH AAAAIAAAGI PVFAVKGETL TEYWDYTAKL 

       130        140        150        160        170        180 
FDWHGGGHPN MILDDGGDAT MYVHLGLRAE NGDTAFLDKP GSEEEEVFFA LLKKQLKEKP 

       190        200        210        220        230        240 
KGYFAEIAKS IKGVSEETTT GVHRLYDMQK AGTLLWPAIN VNDSVTKSKF DNLYGCRESL 

       250        260        270        280        290        300 
VDGIRRGTDV MMSGKVAMVA GFGDVGKGSA ASLRQAGCRV MVSEVDPICA LQAAMEGYEV 

       310        320        330        340        350        360 
VTMEDAAPRA DIFVTATGNK DIITIEHMRA MKDRAIVCNI GHFDNEIQIA GLRNLKWTNI 

       370        380        390        400        410        420 
KPQVDEIEFP DKHRIIMLSE GRLVNLGNAM GHPSFVMSAS FTNQTLAQIE LFANNKDGKY 

       430        440        450        460        470 
KKEVYVLPKT LDEKVARLHL AKIGVKLTEL RKDQADYIGV KQEGPYKSDH YRY
Q89HP6 in FASTA format

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