NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=USDA 110;
DOI=10.1093/dnares/9.6.189; PubMed=12597275 [NCBI, ExPASy, EBI, Israel, Japan]
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110.";
DNA Res. 9:189-197(2002).

Comments

CATALYTIC ACTIVITY: Peptide-L-methionine + thioredoxin disulfide + H₂O = peptide-L-methionine (R)-S-oxide + thioredoxin.
COFACTOR: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein (By similarity).
SIMILARITY: Belongs to the msrB Met sulfoxide reductase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

BA000040; BAC52309.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_773684.1; -.

3D structure databases

HSSP

P14930; 1L1D. [HSSP ENTRY / PDB]

ModBase

Q89EM9.

Enzyme and pathway databases

BioCyc

BJAP224911:BLR7044-MON; -.

Ontologies

GO:0033743;	Molecular function: peptide-methionine (R)-S-oxide reductase activity (inferred from electronic annotation from EC).
GO:0008113;	Molecular function: peptide-methionine-(S)-S-oxide reductase activity (inferred from electronic annotation from HAMAP).
GO:0008270;	Molecular function: zinc ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0055114;	Biological process: oxidation reduction (inferred from electronic annotation from UniProtKB-KW).
QuickGo view.

Family and domain databases

HAMAP

MF_01400; -; 1.
PBIL [Tree]

InterPro

IPR002579; MsrB.
Graphical view of domain structure.

Gene3D

G3DSA:2.170.150.20; MsrB; 1.

Pfam

PF01641; SelR; 1.
Pfam graphical view of domain structure.

ProDom

PD004057; DUF25; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGR00357; MsrB; 1.

Genome annotation databases

GeneID

1047290; -.

GenomeReviews

BA000040_GR; blr7044.

KEGG

bja:blr7044; -.

NMPDR

fig|224911.1.peg.7044; -.

Phylogenomic databases

HOGENOM

Q89EM9; -.

Genome annotation databases

CMR

Q89EM9; blr7044.

Other

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Metal-binding; Oxidoreductase; Zinc.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 139`	`139`	`Peptide methionine sulfoxide reductase msrB.`	`PRO_0000140263`
`ACT_SITE`	`128 128`		`Nucleophile (By similarity).`
`METAL`	`56 56`		`Zinc (By similarity).`
`METAL`	`59 59`		`Zinc (By similarity).`
`METAL`	`105 105`		`Zinc (By similarity).`
`METAL`	`108 108`		`Zinc (By similarity).`

Sequence information

Length: 139 AA [This is the length of the unprocessed precursor]

Molecular weight: 15412 Da [This is the MW of the unprocessed precursor]

CRC64: 6B30220982D09E2A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MPDAKTKTTD DKVIKSEEQW RRELSPIQYA VLREKATERP FSGEYEHDHR AGTYVCAGCG 

        70         80         90        100        110        120 
NVLFESDAKF DSGCGWPSFT QPAVESHVDE ERDVSHGMIR TEVLCAKCSG HLGHVFPDGP 

       130 
GPTGLRYCIN SAALKLEPK

Q89EM9 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools