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UniProtKB/Swiss-Prot entry Q89AM6

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LEP_BUCBP
Primary accession number Q89AM6
Secondary accession numbers None
Integrated into Swiss-Prot on April 13, 2004
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 43)
Name and origin of the protein
Protein name Signal peptidase I
Synonyms SPase I
EC 3.4.21.89
Leader peptidase I
Gene name
Name: lepB
OrderedLocusNames: bbp_240
From
Buchnera aphidicola subsp. Baizongia pistaciae [TaxID: 135842] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0235981100; PubMed=12522265 [NCBI, ExPASy, EBI, Israel, Japan]
van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
"Reductive genome evolution in Buchnera aphidicola.";
Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016826; AAO26967.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_777862.1; -.
3D structure databases
HSSP P00803; 1KN9. [HSSP ENTRY / PDB]
ModBase Q89AM6.
Protein family/group databases
MEROPS S26.001; -.
Enzyme and pathway databases
BioCyc BAPH224915:BBP_240-MON; -.
Ontologies
GO
GO:0016021; Cellular component: integral to membrane (inferred from electronic annotation from InterPro).
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from UniProtKB-KW).
GO:0008236; Molecular function: serine-type peptidase activity (inferred from electronic annotation from InterPro).
GO:0006508; Biological process: proteolysis (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
InterPro IPR000223; Pept_S26A_signal_pept_1.
IPR011056; Peptidase_S24_S26_C.
IPR014037; Peptidase_S26A.
Graphical view of domain structure.
Gene3D G3DSA:2.10.109.10; Pept_S24_S26_C; 1.
PANTHER PTHR12383:SF1; Pept_S26A_signal_pept_1; 1.
PTHR12383; Peptidase_S26A; 1.
Pfam PF00717; Peptidase_S24; 1.
Pfam graphical view of domain structure.
PRINTS PR00727; LEADERPTASE.
TIGRFAMs TIGR02227; sigpep_I_bact; 1.
PROSITE PS00501; SPASE_I_1; 1.
PS00760; SPASE_I_2; 1.
PS00761; SPASE_I_3; 1.
BLOCKS Q89AM6.
ProtoNet Q89AM6.
Genome annotation databases
GeneID 1058242; -.
GenomeReviews AE016826_GR; bbp_240.
KEGG bab:bbp240; -.
Phylogenomic databases
HOGENOM Q89AM6; -.
Genome annotation databases
CMR Q89AM6; bbp_240.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Hydrolase; Membrane; Protease; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   310  310     Signal peptidase I. PRO_0000109505
TRANSMEM   5    25  21     Potential. 
TOPO_DOM   26    57  32     Cytoplasmic (Potential). 
TRANSMEM   58    78  21     Potential. 
TOPO_DOM   79   310  232     Extracellular (Potential). 
ACT_SITE   82    82        By similarity. 
ACT_SITE   137   137        By similarity. 
Sequence information
Length: 310 AA [This is the length of the unprocessed precursor] Molecular weight: 36313 Da [This is the MW of the unprocessed precursor] CRC64: 6CB12207E9CF21B8 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSNYLSSFLL ASSLITGTLW IINKILSHNL LDSKIPFNIK KSKIYYKSKQ VVQTFASFFP 

        70         80         90        100        110        120 
ILIIVFIIRT FICEPFQIPS ESMMPTLLPG DFILVKKFSY GIKNPFSNNV IVFINTPKRG 

       130        140        150        160        170        180 
DIVVFKHPNN NAINYVKRIV GLPGDKINYN ILTKRLTITP NNINEQHTKN ISINYKYIKP 

       190        200        210        220        230        240 
NDFTKHFKLN NIILNNVHSL ESSNNNLLQL EMYQEKIEKI AYNIFFKKKL IDQKDLYFKQ 

       250        260        270        280        290        300 
FSQKQGTWIV PKHKYFVLGD NRDNSLDSRY WGFVPEKNLI GKVVFIWMHL IKKEGQWPTG 

       310 
IQFDRIGNIY
Q89AM6 in FASTA format

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