ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q89AF8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name PNP_BUCBP
Primary accession number Q89AF8
Secondary accession numbers None
Integrated into Swiss-Prot on November 28, 2003
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 43)
Name and origin of the protein
Protein name Polyribonucleotide nucleotidyltransferase
Synonyms EC 2.7.7.8
Polynucleotide phosphorylase
PNPase
Gene name
Name: pnp
OrderedLocusNames: bbp_336
From
Buchnera aphidicola subsp. Baizongia pistaciae [TaxID: 135842] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Buchnera.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0235981100; PubMed=12522265 [NCBI, ExPASy, EBI, Israel, Japan]
van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
"Reductive genome evolution in Buchnera aphidicola.";
Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016826; AAO27057.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_777952.1; -.
3D structure databases
HSSP P05055; 1SRO. [HSSP ENTRY / PDB]
SMR Q89AF8; 617-692.
ModBase Q89AF8.
Enzyme and pathway databases
BioCyc BAPH224915:BBP_336-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0000175; Molecular function: 3'-5'-exoribonuclease activity (inferred from electronic annotation from InterPro).
GO:0004654; Molecular function: polyribonucleotide nucleotidyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0003723; Molecular function: RNA binding (inferred from electronic annotation from InterPro).
GO:0006402; Biological process: mRNA catabolic process (inferred from electronic annotation from HAMAP).
GO:0006396; Biological process: RNA processing (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_01595; -; 1.
PBIL [Tree]
InterPro IPR001247; ExoRNase_PH_dom1.
IPR015847; ExoRNase_PH_dom2.
IPR004087; KH.
IPR004088; KH_type_1.
IPR012340; NA-bd_OB-fold.
IPR012162; PNPase.
IPR015848; PNPase_PH_RNA-bd_bac/org-type.
IPR003029; S1_RNA-bd.
Graphical view of domain structure.
Gene3D G3DSA:2.40.50.140; OB_NA_bd_sub; 1.
G3DSA:1.10.10.400; PNPase_PH_RNA-bd_bac/org-type; 1.
PANTHER PTHR11252; PNPase; 1.
Pfam PF00013; KH_1; 1.
PF03726; PNPase; 1.
PF01138; RNase_PH; 2.
PF03725; RNase_PH_C; 2.
PF00575; S1; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF005499; PNPase; 1.
SMART SM00322; KH; 1.
SM00316; S1; 1.
SMART graphical view of domain structure.
PROSITE PS50084; KH_TYPE_1; 1.
PS50126; S1; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS Q89AF8.
ProtoNet Q89AF8.
Genome annotation databases
GeneID 1058421; -.
GenomeReviews AE016826_GR; bbp_336.
KEGG bab:bbp336; -.
Phylogenomic databases
HOGENOM Q89AF8; -.
Genome annotation databases
CMR Q89AF8; bbp_336.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Nucleotidyltransferase; RNA-binding; Transferase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   693  693     Polyribonucleotide nucleotidyltransferase. PRO_0000197912
DOMAIN   553   612  60     KH. 
DOMAIN   622   690  69     S1 motif. 
Sequence information
Length: 693 AA [This is the length of the unprocessed precursor] Molecular weight: 77000 Da [This is the MW of the unprocessed precursor] CRC64: 448E952C478C339B [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MLNPIVRKFQ YGQHIVTLET GIMARQATAA VLTSMDDTTV FVTVVGQKKL QTEQKFFPMT 

        70         80         90        100        110        120 
VNYQERTYAA GRIPGGFFRR EGRPSENEIL IARLIDRPIR PLFPKRFFNE VQIIATVVSL 

       130        140        150        160        170        180 
NPQVNPDIVA IIGASAALSI SGMPFLGPIG AARIGYINNQ YILNPNVNEI KSSSLDLIIS 

       190        200        210        220        230        240 
GTEESVLMVE AEANMLTEEQ IINAINYGHE QQKIVIKNIE HFAKKVKIPV WEQCLYPVND 

       250        260        270        280        290        300 
DLEKRIIEIS EQEIVKAYNI FDKVIRLDVL DKIKSKAIEI IISEYSGIDE FEITSIISNI 

       310        320        330        340        350        360 
ERKIVRNRVL KNRIRIDGRN KDEIRTLDVR TGVLPRVHGS ALFTRGETQS LVSVTLGTSR 

       370        380        390        400        410        420 
DAQNLDELLG DKTDNFLFHY NFPPYAVGEI GMVGSPKRRE IGHGKLAKRS ILAVMPKLDL 

       430        440        450        460        470        480 
FPYTIRIVSE ITESNGSSSM ASVCGASLAL MDAGVPISNA IAGIAMGLIK EGDDFVVLTD 

       490        500        510        520        530        540 
ILGDEDHLGD MDFKISGSKK GITALQMDIK VKGITNEIMK LALYQAKNAR IHILNIMKKS 

       550        560        570        580        590        600 
LNVPRKDISI FAPRIHTIKI NPEKIKDVIG KGGSVIRMLT EETGTTIEIE DDGTVKISAV 

       610        620        630        640        650        660 
MQEKAKCAIQ RIKEITAEVE VGSVYTGKVT RIVDFGAFVS IGIGKEGLVH ISQIAHKRVD 

       670        680        690 
KVSDHLRLHQ EIFVKVLEVD RQGRLRLSIK GAK
Q89AF8 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by au flag APAF Australia Mirror sites: Brazil Canada China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!