ID   MTLD_BUCBP              Reviewed;         390 AA.
AC   Q89A37;
DT   23-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-MAY-2003, sequence version 1.
DT   25-NOV-2008, entry version 32.
DE   RecName: Full=Mannitol-1-phosphate 5-dehydrogenase;
DE            EC=1.1.1.17;
GN   Name=mtlD; OrderedLocusNames=bbp_516;
OS   Buchnera aphidicola subsp. Baizongia pistaciae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Buchnera.
OX   NCBI_TaxID=135842;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   MEDLINE=22426901; PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- CATALYTIC ACTIVITY: D-mannitol 1-phosphate + NAD(+) = D-fructose
CC       6-phosphate + NADH.
CC   -!- SIMILARITY: Belongs to the mannitol dehydrogenase family.
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DR   EMBL; AE016826; AAO27219.1; -; Genomic_DNA.
DR   RefSeq; NP_778114.1; -.
DR   GeneID; 1058182; -.
DR   GenomeReviews; AE016826_GR; bbp_516.
DR   KEGG; bab:bbp516; -.
DR   HOGENOM; Q89A37; -.
DR   BioCyc; BAPH224915:BBP_516-MON; -.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0008926; F:mannitol-1-phosphate 5-dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00196; -; 1.
DR   InterPro; IPR013328; DHase_multihelical.
DR   InterPro; IPR013118; Mannitol_DHase_C.
DR   InterPro; IPR000669; Mannitol_DHase_core.
DR   InterPro; IPR013131; Mannitol_DHase_N.
DR   InterPro; IPR016040; NAD(P)-bd.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   PROSITE; PS00974; MANNITOL_DHGENASE; FALSE_NEG.
PE   3: Inferred from homology;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    390       Mannitol-1-phosphate 5-dehydrogenase.
FT                                /FTId=PRO_0000170701.
FT   NP_BIND       3     14       NAD (By similarity).
SQ   SEQUENCE   390 AA;  44567 MW;  B1037CA82DC02E8D CRC64;
     MNALHFGAGN IGRGFIGPLL LKSGFNLTFV DNNQAIVDAI NRHQKYDITV VGNNFSYITT
     VKKVKAIYIN DPNIYFKIAK INVITISVGV HAINSLVVFF EKLIRYKIET NDFVFLTIIA
     CENVFRCASK LKENIKILLP GIYHKYLDKN ISFVDSVVDK IVCPNDKNNS DDINLSVKVE
     KFSEWIVDCT QFKHDRPNII GMIYSNHLDA FFERKLFTLN TGHAIAAYLG LLIGYKNIYQ
     AILDPLIFNI VYGAMKESGM VLIRKYNFFT DSEHKNYILK ILSRFKNIYL TDSLKRVGRN
     PLQKLKKDDR LISPLIDTIK YNLPNANLMK GIAAALCYID EKDIEAKKLR NMIINKGIKY
     VLSKISSLDS SLLIISEISI YFNIFMKVNI
//