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UniProtKB/Swiss-Prot entry Q890Z2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name K6PF_CLOTE
Primary accession number Q890Z2
Secondary accession numbers None
Integrated into Swiss-Prot on June 16, 2003
Sequence was last modified on June 16, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 39)
Name and origin of the protein
Protein name 6-phosphofructokinase
Synonyms Phosphofructokinase
EC 2.7.1.11
Phosphohexokinase
Gene name
Name: pfkA
OrderedLocusNames: CTC_02490
From
Clostridium tetani [TaxID: 1513] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Clostridia; Clostridiales; Clostridiaceae; Clostridium.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Massachusetts / E88;
DOI=10.1073/pnas.0335853100; PubMed=12552129 [NCBI, ExPASy, EBI, Israel, Japan]
Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I., Herzberg C., Martinez-Arias R., Merkl R., Henne A., Gottschalk G.;
"The genome sequence of Clostridium tetani, the causative agent of tetanus disease.";
Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE015927; AAO36953.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_783016.1; -.
3D structure databases
HSSP P00512; 6PFK. [HSSP ENTRY / PDB]
ModBase Q890Z2.
Enzyme and pathway databases
BioCyc CTET212717:CTC_02490-MON; -.
Ontologies
GO
GO:0005945; Cellular component: 6-phosphofructokinase complex (inferred from electronic annotation from InterPro).
GO:0003872; Molecular function: 6-phosphofructokinase activity (inferred from electronic annotation from HAMAP).
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from InterPro).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0006002; Biological process: fructose 6-phosphate metabolic process (inferred from electronic annotation from InterPro).
GO:0006096; Biological process: glycolysis (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00339; -; 1.
PBIL [Tree]
InterPro IPR012003; ATP_PFK_prok.
IPR012828; PFKA_ATP.
IPR015912; Phosphofructokinase_CS.
IPR000023; Ppfruckinase.
Graphical view of domain structure.
PANTHER PTHR13697; Ppfruckinase; 1.
Pfam PF00365; PFK; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000532; ATP_PFK_prok; 1.
PRINTS PR00476; PHFRCTKINASE.
ProDom PD000707; Ppfruckinase; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR02482; PFKA_ATP; 1.
PROSITE PS00433; PHOSPHOFRUCTOKINASE; 1.
BLOCKS Q890Z2.
ProtoNet Q890Z2.
Genome annotation databases
GeneID 1060662; -.
GenomeReviews AE015927_GR; CTC_02490.
KEGG ctc:CTC02490; -.
NMPDR fig|212717.1.peg.2238; -.
Phylogenomic databases
HOGENOM Q890Z2; -.
Genome annotation databases
CMR Q890Z2; CTC_02490.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Allosteric enzyme; ATP-binding; Complete proteome; Cytoplasm; Glycolysis; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   319  319     6-phosphofructokinase. PRO_0000111946
NP_BIND   21    25  5     ATP (By similarity). 
NP_BIND   154   158  5     ATP (By similarity). 
NP_BIND   171   187  17     ATP (By similarity). 
ACT_SITE   127   127        Proton acceptor (By similarity). 
METAL   185   185        Magnesium; via carbonyl oxygen (By similarity). 
METAL   187   187        Magnesium (By similarity). 
BINDING   162   162        Substrate (By similarity). 
BINDING   243   243        Substrate (By similarity). 
BINDING   249   249        Substrate (By similarity). 
BINDING   252   252        Substrate (By similarity). 
Sequence information
Length: 319 AA [This is the length of the unprocessed precursor] Molecular weight: 34002 Da [This is the MW of the unprocessed precursor] CRC64: A29A5DDDB89C216F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MRKIAVLTSG GDAPGMNAAI RAVVRTGLDK GITVLGIERG FDGLLNGEIF EMTRRSVADI 

        70         80         90        100        110        120 
IQRGGTILRT ARSEEFKTEE GQKKATDILR VFGVEGLVVI GGDGSFQGAK SLSELGVKTI 

       130        140        150        160        170        180 
GIPGTIDNDL AYTDYTIGFD TAVNTVLDAI NKLRDTSTSH GRASVVEVMG RNCGDIALYA 

       190        200        210        220        230        240 
GLAGGAESII VPELRFDIDK LCKTILEGKK NGKMHNLIIV AEGAGKANDI AKTIEKVTGV 

       250        260        270        280        290        300 
GTRATVLGHI QRGGSPTAND RILASRMGNR AVELLLEEKS SRVVGINDNR IVDMDIHEAL 

       310 
SIEGKFDEKL YEIAKALSY
Q890Z2 in FASTA format

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