ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry Q890C2

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name THIM_LACPL
Primary accession number Q890C2
Secondary accession numbers None
Integrated into Swiss-Prot on October 31, 2003
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 41)
Name and origin of the protein
Protein name Hydroxyethylthiazole kinase
Synonyms EC 2.7.1.50
4-methyl-5-beta-hydroxyethylthiazole kinase
Thz kinase
TH kinase
Gene name
Name: thiM
OrderedLocusNames: lp_0113
From
Lactobacillus plantarum [TaxID: 1590] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
DOI=10.1073/pnas.0337704100; PubMed=12566566 [NCBI, ExPASy, EBI, Israel, Japan]
Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M., Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M., Siezen R.J.;
"Complete genome sequence of Lactobacillus plantarum WCFS1.";
Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL935252; CAD62792.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_783954.1; -.
3D structure databases
HSSP P39593; 1EKQ. [HSSP ENTRY / PDB]
ModBase Q890C2.
Enzyme and pathway databases
BioCyc LPLA220668:LP_0113-MON; -.
Ontologies
GO
GO:0005524; Molecular function: ATP binding (inferred from electronic annotation from HAMAP).
GO:0004417; Molecular function: hydroxyethylthiazole kinase activity (inferred from electronic annotation from HAMAP).
GO:0000287; Molecular function: magnesium ion binding (inferred from electronic annotation from UniProtKB-KW).
GO:0009228; Biological process: thiamin biosynthetic process (inferred from electronic annotation from InterPro).
QuickGo view.
Family and domain databases
HAMAP MF_00228; -; 1.
PBIL [Tree]
InterPro IPR000417; Hyethyz_kinase.
IPR011144; Hyethyz_kinsmonf.
Graphical view of domain structure.
PANTHER PTHR20857:SF14; Hyethyz_kinase; 1.
Pfam PF02110; HK; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000513; Thz_kinase; 1.
PRINTS PR01099; HYETHTZKNASE.
BLOCKS Q890C2.
ProtoNet Q890C2.
Genome annotation databases
GeneID 1061358; -.
GenomeReviews AL935263_GR; lp_0113.
KEGG lpl:lp_0113; -.
NMPDR fig|220668.1.peg.88; -.
Phylogenomic databases
HOGENOM Q890C2; -.
Genome annotation databases
CMR Q890C2; lp_0113.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
ATP-binding; Complete proteome; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Thiamine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   263  263     Hydroxyethylthiazole kinase. PRO_0000156940
METAL   90    90        Magnesium 1 (By similarity). 
METAL   122   122        Magnesium 1 (By similarity). 
BINDING   41    41        Substrate; via amide nitrogen (By similarity). 
BINDING   117   117        ATP (By similarity). 
BINDING   163   163        ATP (By similarity). 
BINDING   190   190        Substrate; via amide nitrogen (By similarity). 
Sequence information
Length: 263 AA [This is the length of the unprocessed precursor] Molecular weight: 27521 Da [This is the MW of the unprocessed precursor] CRC64: CC4E65F7DC6FF44F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MELQLLNTLR NHNPIVFNIA NFVTVQDVAN GLNALGASPI MSAEVQEAET MVQIAGAVCI 

        70         80         90        100        110        120 
NLGTLTTTQI DQMRVVGKLA NQYHKPVVLD PVAVGAVPYR KEVALALLSD FQVDVIRGNA 

       130        140        150        160        170        180 
GEIAALAGMD WQAKGIDAGS GQGDLVEIAQ ACAQQFQCCV ILSGPTDVIT DGQRVVKVAN 

       190        200        210        220        230        240 
GTPLFQRHVG SGDLLSSIVA AFTAVSPTDV YQAAQVACLV LAGAGELVAS QLTADRPATF 

       250        260 
AIDLIDRLSL VTVSEIQTIA KVD
Q890C2 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by au flag APAF Australia Mirror sites: Brazil Canada China Korea Switzerland
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!