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UniProtKB/Swiss-Prot entry Q88SV5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GUAC_LACPL
Primary accession number Q88SV5
Secondary accession numbers None
Integrated into Swiss-Prot on March 15, 2004
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 35)
Name and origin of the protein
Protein name GMP reductase
Synonyms EC 1.7.1.7
Guanosine 5'-monophosphate oxidoreductase
Guanosine monophosphate reductase
Gene name
Name: guaC
OrderedLocusNames: lp_3271
From
Lactobacillus plantarum [TaxID: 1590] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Lactobacillales; Lactobacillaceae; Lactobacillus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC BAA-793 / NCIMB 8826 / WCFS1;
DOI=10.1073/pnas.0337704100; PubMed=12566566 [NCBI, ExPASy, EBI, Israel, Japan]
Kleerebezem M., Boekhorst J., van Kranenburg R., Molenaar D., Kuipers O.P., Leer R., Tarchini R., Peters S.A., Sandbrink H.M., Fiers M.W.E.J., Stiekema W., Klein Lankhorst R.M., Bron P.A., Hoffer S.M., Nierop Groot M.N., Kerkhoven R., De Vries M., Ursing B., De Vos W.M., Siezen R.J.;
"Complete genome sequence of Lactobacillus plantarum WCFS1.";
Proc. Natl. Acad. Sci. U.S.A. 100:1990-1995(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AL935261; CAD65404.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_786532.1; -.
3D structure databases
HSSP P12268; 1B3O. [HSSP ENTRY / PDB]
SMR Q88SV5; 5-321.
ModBase Q88SV5.
Enzyme and pathway databases
BioCyc LPLA220668:LP_3271-MON; -.
Ontologies
GO
GO:0003920; Molecular function: GMP reductase activity (inferred from electronic annotation from HAMAP).
GO:0055114; Biological process: oxidation reduction (inferred from electronic annotation from InterPro).
GO:0006163; Biological process: purine nucleotide metabolic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01511; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR005994; GMP_reduct2.
IPR015875; IMP_DH/GMP_Rdtase_CS.
IPR001093; IMP_DHase_GMPRtase.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
Pfam PF00478; IMPDH; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF036500; GMP_red_Firmic; 1.
TIGRFAMs TIGR01306; GMP_reduct_2; 1.
PROSITE PS00487; IMP_DH_GMP_RED; 1.
BLOCKS Q88SV5.
ProtoNet Q88SV5.
Genome annotation databases
GeneID 1061982; -.
GenomeReviews AL935263_GR; lp_3271.
KEGG lpl:lp_3271; -.
NMPDR fig|220668.1.peg.2666; -.
Phylogenomic databases
HOGENOM Q88SV5; -.
Genome annotation databases
CMR Q88SV5; lp_3271.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   325  325     GMP reductase. PRO_0000093760
NP_BIND   205   228  24     NADP (By similarity). 
ACT_SITE   176   176        Thioimidate intermediate (By similarity). 
Sequence information
Length: 325 AA [This is the length of the unprocessed precursor] Molecular weight: 35432 Da [This is the MW of the unprocessed precursor] CRC64: E19846BECA12DBE6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MGMEIFDYED IQLIPNKCVI NSRSEADTTV ELGGRRFKIP VVPANMATVI NDEIAKWLAT 

        70         80         90        100        110        120 
NDYFYIMHRF APETRRAFIE TMHAAQLYAS ISVGVKSSEY DFIDDLATNQ IVPEYITIDI 

       130        140        150        160        170        180 
AHGHADSVIA MIKHIKDVLP DSFVIAGNVA TPAAVRDLEN AGADATKVGV GPGKACITKV 

       190        200        210        220        230        240 
KTGFGTGGWQ LAAVRWCAKA ARKPIIADGG VRTNGDIAKS IRFGATMVMI GSMLAGHQES 

       250        260        270        280        290        300 
PGNILKIDGK TYKQYYGSAS ETQKGEHKNV EGKQMLVPYR GRLVDTLNEM QEDLQSSISY 

       310        320 
AGGRDLKAIT KCDYVVVKNS IYNGD 

Q88SV5 in FASTA format

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