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UniProtKB/Swiss-Prot entry Q88QA3


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ADD_PSEPK
Primary accession number Q88QA3
Secondary accession numbers None
Integrated into Swiss-Prot on October 31, 2003
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 28)
Name and origin of the protein
Protein name Adenosine deaminase
Synonyms EC 3.5.4.4
Adenosine aminohydrolase
Gene name
Name: add
OrderedLocusNames: PP_0591
From
Pseudomonas putida (strain KT2440) [TaxID: 160488] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1046/j.1462-2920.2002.00366.x; PubMed=12534463 [NCBI, ExPASy, EBI, Israel, Japan]
Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H., Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M., Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F., Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M., Hance I., Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A., Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M.;
"Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440.";
Environ. Microbiol. 4:799-808(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE015451; AAN66218.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_742754.1; -.
3D structure databases
ModBase Q88QA3.
Enzyme and pathway databases
BioCyc PPUT160488:PP_0591-MON; -.
Ontologies
GO
GO:0004000; Molecular function: adenosine deaminase activity (inferred from electronic annotation from HAMAP).
GO:0009168; Biological process: purine ribonucleoside monophosphate biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00540; -; 1.
PBIL [Tree]
InterPro IPR006650; A/AMP_deam_AS.
IPR001365; A/AMP_deaminase.
IPR006330; A_deaminase.
Graphical view of domain structure.
PANTHER PTHR11409; A/AMP_deaminase; 1.
Pfam PF00962; A_deaminase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01430; aden_deam; 1.
PROSITE PS00485; A_DEAMINASE; FALSE_NEG.
BLOCKS Q88QA3.
ProtoNet Q88QA3.
Genome annotation databases
GeneID 1044402; -.
GenomeReviews AE015451_GR; PP_0591.
KEGG ppu:PP_0591; -.
NMPDR fig|160488.1.peg.584; -.
TIGR PP_0591; -.
Phylogenomic databases
HOGENOM Q88QA3; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Nucleotide metabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   315  315     Adenosine deaminase. PRO_0000194378
ACT_SITE   194   194        Potential. 
ACT_SITE   242   242        Potential. 
ACT_SITE   275   275        Potential. 
ACT_SITE   276   276        Potential. 
Sequence information
Length: 315 AA [This is the length of the unprocessed precursor] Molecular weight: 35846 Da [This is the MW of the unprocessed precursor] CRC64: 78D54FA84F9E93D5 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MYDWLNALPK AELHLHLEGS LEPELLFALA ERNKIALPWA DVETLRGAYA FNNLQEFLDL 

        70         80         90        100        110        120 
YYQGADVLRT EQDFYDLTWA YLQRCKAQNV IHTEPFFDPQ THTDRGIAFE VVLNGISQAL 

       130        140        150        160        170        180 
KDGREQLGIS SGLILSFLRH LSEDEAQKTL DQALPFRDAF IAVGLDSSEM GHPPSKFQRV 

       190        200        210        220        230        240 
FDRARSEGFV AVAHAGEEGP PEYIWEALDL LKIKRIDHGV RAIEDERLMQ RIIDEQIPLT 

       250        260        270        280        290        300 
VCPLSNTKLC VFDHMSQHNI LDMLERGVKV TVNSDDPAYF GGYVTENFHA LHTHLGMTED 

       310 
QARRLAQNSL DARLV 

Q88QA3 in FASTA format

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