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UniProtKB/Swiss-Prot entry Q88JY1


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GCH12_PSEPK
Primary accession number Q88JY1
Secondary accession numbers None
Integrated into Swiss-Prot on January 16, 2004
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 37)
Name and origin of the protein
Protein name GTP cyclohydrolase 1 2
Synonyms EC 3.5.4.16
GTP cyclohydrolase I 2
GTP-CH-I 2
Gene name
Name: folE2
OrderedLocusNames: PP_2512
From
Pseudomonas putida (strain KT2440) [TaxID: 160488] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1046/j.1462-2920.2002.00366.x; PubMed=12534463 [NCBI, ExPASy, EBI, Israel, Japan]
Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H., Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M., Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F., Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M., Hance I., Chris Lee P., Holtzapple E.K., Scanlan D., Tran K., Moazzez A., Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D., Wedler H., Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S., Kiewitz C., Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B., Fraser C.M.;
"Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440.";
Environ. Microbiol. 4:799-808(2002).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE015451; AAN68124.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_744660.1; -.
3D structure databases
HSSP P22288; 1IS7. [HSSP ENTRY / PDB]
ModBase Q88JY1.
Enzyme and pathway databases
BioCyc PPUT160488:PP_2512-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from InterPro).
GO:0003934; Molecular function: GTP cyclohydrolase I activity (inferred from electronic annotation from HAMAP).
GO:0019438; Biological process: aromatic compound biosynthetic process (inferred from electronic annotation from InterPro).
GO:0006730; Biological process: one-carbon compound metabolic process (inferred from electronic annotation from HAMAP).
GO:0046654; Biological process: tetrahydrofolate biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00223; -; 1.
PBIL [Tree]
InterPro IPR001474; GTP_CycOHase_I.
Graphical view of domain structure.
PANTHER PTHR11109; GTP_cyclohydro_I; 1.
Pfam PF01227; GTP_cyclohydroI; 1.
Pfam graphical view of domain structure.
ProDom PD003330; GTP_cyclohydroI; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00063; folE; 1.
PROSITE PS00859; GTP_CYCLOHYDROL_1_1; 1.
PS00860; GTP_CYCLOHYDROL_1_2; 1.
BLOCKS Q88JY1.
ProtoNet Q88JY1.
Genome annotation databases
GeneID 1045754; -.
GenomeReviews AE015451_GR; PP_2512.
KEGG ppu:PP_2512; -.
NMPDR fig|160488.1.peg.2490; -.
TIGR PP_2512; -.
Phylogenomic databases
HOGENOM Q88JY1; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; One-carbon metabolism.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   186  186     GTP cyclohydrolase 1 2. PRO_0000119431
Sequence information
Length: 186 AA [This is the length of the unprocessed precursor] Molecular weight: 20886 Da [This is the MW of the unprocessed precursor] CRC64: D4F2562CC214F0F7 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSHSLAEHYH EILVGIGENP QREGLLDTPR RAAKAMQYLC NGYAQDLHEV VNGALFESEN 

        70         80         90        100        110        120 
DEMIVVRDIE LYSLCEHHML PFIGKAHVAY LPTGRVLGLS KVARVVDMFA RRLQIQENLT 

       130        140        150        160        170        180 
RQIAYAVQEV TDAAGVGVVI EAKHMCMMMR GVEKQNSVMI SSVMLGAFRD APSTRHEFLN 


LIGRHN 

Q88JY1 in FASTA format

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