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UniProtKB/Swiss-Prot entry Q88AR1

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name GSH1_PSESM
Primary accession number Q88AR1
Secondary accession numbers None
Integrated into Swiss-Prot on March 1, 2004
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Glutamate--cysteine ligase
Synonyms EC 6.3.2.2
Gamma-glutamylcysteine synthetase
Gamma-ECS
GCS
Gene name
Name: gshA
OrderedLocusNames: PSPTO_0325
From
Pseudomonas syringae pv. tomato [TaxID: 323] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=DC3000;
DOI=10.1073/pnas.1731982100; PubMed=12928499 [NCBI, ExPASy, EBI, Israel, Japan]
Buell C.R., Joardar V., Lindeberg M., Selengut J., Paulsen I.T., Gwinn M.L., Dodson R.J., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R., Daugherty S.C., Brinkac L.M., Beanan M.J., Haft D.H., Nelson W.C., Davidsen T.M., Zafar N., Zhou L., Liu J., Yuan Q., Khouri H.M., Fedorova N.B., Tran B., Russell D., Berry K.J., Utterback T.R., Van Aken S.E., Feldblyum T.V., D'Ascenzo M., Deng W.-L., Ramos A.R., Alfano J.R., Cartinhour S., Chatterjee A.K., Delaney T.P., Lazarowitz S.G., Martin G.B., Schneider D.J., Tang X., Bender C.L., White O., Fraser C.M., Collmer A.;
"The complete genome sequence of the Arabidopsis and tomato pathogen Pseudomonas syringae pv. tomato DC3000.";
Proc. Natl. Acad. Sci. U.S.A. 100:10181-10186(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016853; AAO53870.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_790175.1; -.
3D structure databases
ModBase Q88AR1.
Enzyme and pathway databases
BioCyc PSYR223283:PSPTO_0325-MON; -.
Ontologies
GO
GO:0004357; Molecular function: glutamate-cysteine ligase activity (inferred from electronic annotation from HAMAP).
GO:0006750; Biological process: glutathione biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00578; -; 1.
PBIL [Tree]
InterPro IPR007370; Glu_cys_ligase.
IPR006334; Glut_cys_ligase.
Graphical view of domain structure.
Pfam PF04262; Glu_cys_ligase; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR01434; glu_cys_ligase; 1.
BLOCKS Q88AR1.
ProtoNet Q88AR1.
Genome annotation databases
GeneID 1181934; -.
GenomeReviews AE016853_GR; PSPTO_0325.
KEGG pst:PSPTO_0325; -.
NMPDR fig|223283.1.peg.313; -.
TIGR PSPTO_0325; -.
Phylogenomic databases
HOGENOM Q88AR1; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Glutathione biosynthesis; Ligase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   529  529     Glutamate--cysteine ligase. PRO_0000192534
Sequence information
Length: 529 AA [This is the length of the unprocessed precursor] Molecular weight: 59495 Da [This is the MW of the unprocessed precursor] CRC64: CA3A6DBC708BC2FA [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSELLNRRLA LLGERNNLSL LEQCLHGIER ECLRVTPQAE LARTPHPQAL GAALTNGLVT 

        70         80         90        100        110        120 
TDYSESLLEF ITPALKNPVD TLDSLDKIHR FAYSKLDNEL LWSPSMPCPL PDEEHIPIAY 

       130        140        150        160        170        180 
YGTSNIGKLK YVYRKGLALR YGKTMQCIAG IHYNFSLPED AWALLKQTED FAGDARDYQS 

       190        200        210        220        230        240 
HSYIALIRNF RRYSWLLMYL FGASPALDAG FLRGREHQLE QFDADTLYLP YATSLRMSDL 

       250        260        270        280        290        300 
GYQSDAQADL TPCYNDLVSY TDSLRKAVAT PYKPYVDIGT HDQNGEWVQL NTNVLQIENE 

       310        320        330        340        350        360 
YYSNIRPKRV TYSGERPIQA LVARGVQYVE VRCLDINPFL PTGISLEQSR FIDAFVLYCA 

       370        380        390        400        410        420 
LEESQQLAGH ECSNASSNFL AVVKEGRRPG LNLQRDDSPV ELKAWATDLL EKITPIARLL 

       430        440        450        460        470        480 
DQAQGTDEHI KSIAVQQAKI DDTSLTPSAQ VLASMRAHGE GFTAFSLRQS QVHAEYFRTH 

       490        500        510        520 
PLSAAEQAHF EDLAKTSLEE QAELEATEEV VDFDTFVGSY QASILSISN
Q88AR1 in FASTA format

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