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UniProtKB/Swiss-Prot entry Q81T69


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC1_BACAN
Primary accession number Q81T69
Secondary accession numbers Q6I1F2 Q6KV98
Integrated into Swiss-Prot on July 19, 2004
Sequence was last modified on June 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 37)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase 1
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase 1
Alpha-keto-beta-hydroxylacil reductoisomerase 1
Gene name
Name: ilvC1
Synonyms: ilvC-1
OrderedLocusNames: BA_1419, GBAA1419, BAS1310
From
Bacillus anthracis [TaxID: 1392] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Ames / isolate Porton;
DOI=10.1038/nature01586; PubMed=12721629 [NCBI, ExPASy, EBI, Israel, Japan]
Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.;
"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria.";
Nature 423:81-86(2003).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Ames ancestor;
Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M.;
"Bacillus anthracis comparative genomics.";
Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Sterne;
Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.;
"Complete genome sequence of Bacillus anthracis Sterne.";
Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE016879; AAP25362.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE017334; AAT30515.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE017225; AAT53630.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_843876.1; -.
YP_018040.1; -.
YP_027579.1; -.
3D structure databases
HSSP Q9HVA2; 1NP3. [HSSP ENTRY / PDB]
ModBase Q81T69.
Enzyme and pathway databases
BioCyc BANT260799:BAS1310-MON; -.
BANT261594:GBAA1419-MON; -.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013116; IlvN.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS Q81T69.
Genome annotation databases
GeneID 1084747; -.
2816383; -.
2851032; -.
GenomeReviews AE016879_GR; BA_1419.
AE017225_GR; BAS1310.
AE017334_GR; GBAA1419.
KEGG ban:BA1419; -.
bar:GBAA1419; -.
bat:BAS1310; -.
TIGR BA_1419; -.
GBAA1419; -.
Phylogenomic databases
HOGENOM Q81T69; -.
Other
ProtoNet Q81T69.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   336  336     Ketol-acid reductoisomerase 1. PRO_0000151270
ACT_SITE   107   107        Potential. 
Sequence information
Length: 336 AA [This is the length of the unprocessed precursor] Molecular weight: 36693 Da [This is the MW of the unprocessed precursor] CRC64: 9AC603888E73FF3E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAKVYYEKDV TVNVLKEKKV AIIGYGSQGH AHAQNLRDNG FDVVVGLRKG KSWDKAKEDG 

        70         80         90        100        110        120 
FSVYTVAEAA KQADVVMILL PDELQPEVYE EEIAPNLQAG NSLVFAHGFN VHFDQVKPPV 

       130        140        150        160        170        180 
NVDVFLVAPK GPGHLVRRTF SEGGAVPALF AVYQDATGVA TEKALSYADG IGATRAGVLE 

       190        200        210        220        230        240 
TTFKEETETD LFGEQAVLCG GVTALVKAGF ETLVDAGYQP ELAYFECLHE LKLIVDLMYE 

       250        260        270        280        290        300 
GGLENMRYSV SDTAQWGDFV SGPRVVTEDT KKAMGTVLAE IQDGTFARGW IAEHKAGKPN 

       310        320        330 
FYATNEKENE HEIEVVGRKL RGMMPFVQPR VKAGVK 

Q81T69 in FASTA format

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