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UniProtKB/Swiss-Prot entry Q7WHW8

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DNAE2_BORBR
Primary accession number Q7WHW8
Secondary accession numbers None
Integrated into Swiss-Prot on July 19, 2005
Sequence was last modified on October 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 31)
Name and origin of the protein
Protein name Error-prone DNA polymerase
Synonym EC 2.7.7.7
Gene name
Name: dnaE2
OrderedLocusNames: BB3088
From
Bordetella bronchiseptica (Alcaligenes bronchisepticus) [TaxID: 518] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=RB50 / ATCC BAA-588 / NCTC 13252;
DOI=10.1038/ng1227; PubMed=12910271 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.";
Nat. Genet. 35:32-40(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX640446; CAE33580.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_889624.1; -.
3D structure databases
ModBase Q7WHW8.
Enzyme and pathway databases
BioCyc BBRO257310:BB3088-MON; -.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0003887; Molecular function: DNA-directed DNA polymerase activity (inferred from electronic annotation from HAMAP).
GO:0045020; Biological process: error-prone DNA repair (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01902; -; 1.
PBIL [Tree]
InterPro IPR011708; DNA_pol3_alpha.
IPR004365; NA_bd_OB_tRNA-helicase.
IPR004013; PHP_C.
IPR003141; PHP_N.
IPR004805; PolC_alpha.
Graphical view of domain structure.
Pfam PF07733; DNA_pol3_alpha; 1.
PF02811; PHP; 1.
PF01336; tRNA_anti; 1.
Pfam graphical view of domain structure.
SMART SM00481; POLIIIAc; 1.
SMART graphical view of domain structure.
TIGRFAMs TIGR00594; polc; 1.
BLOCKS Q7WHW8.
Genome annotation databases
GeneID 2663274; -.
GenomeReviews BX470250_GR; BB3088.
KEGG bbr:BB3088; -.
NMPDR fig|257310.1.peg.3071; -.
Phylogenomic databases
HOGENOM Q7WHW8; -.
Genome annotation databases
CMR Q7WHW8; BB3088.
Other
ProtoNet Q7WHW8.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; DNA damage; DNA repair; DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   1052  1052     Error-prone DNA polymerase. PRO_0000103367
Sequence information
Length: 1052 AA [This is the length of the unprocessed precursor] Molecular weight: 115105 Da [This is the MW of the unprocessed precursor] CRC64: D95FADC2CA5D656F [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSAILPGYAE LHCQSNFSFL QGASHPEELV TRAGELGYAA LALTDECSLA GVVRAHVEAR 

        70         80         90        100        110        120 
EQKLPLIIGS SFTLQAGADA PPLDLTLLAQ NREGYGNLAE LITLGRGRAA KGQYLLTPAD 

       130        140        150        160        170        180 
IEAPAGDNAH LRGMPDCLAI LAPPPGLAAE RLAEQARWLA AQCPGRAWIG LTLLHHCRDD 

       190        200        210        220        230        240 
LHRAAVEHAA HASGLPIVAL GQAQMHRRSR KPLHDTLAAI RTGRSVGQCG YDLAANAERH 

       250        260        270        280        290        300 
LRSRLRLASL YPAQALAQTL AIARRCTFSL DELQYEYPDE IVPAGHTPAS YLRQQTYLGA 

       310        320        330        340        350        360 
RQRFPEGMTP AVAAQVEKEL ALINELRYEA YFLTVYDIVG YARSQGILCQ GRGSAANSAV 

       370        380        390        400        410        420 
CYCLGITAVD PARGNTLFER FISKERNEPP DIDVDFEHQR REEVIQYIYE KYGRQRAALT 

       430        440        450        460        470        480 
AVVISYRPRS VLRDTGRALG VDNGIIDAVA RAHQWWDGKK EMLRSLAACG LDPASRVARQ 

       490        500        510        520        530        540 
WAELAETLMG FPRHLSQHPG GFVISRGKLS RLVPIENAAM PGRSVVQWDK DDLDALRLLK 

       550        560        570        580        590        600 
VDVLALGMLS VLRRALALAG QRRGRPLALH EIPPDDDATY DMICAADTIG VFQIESRAQM 

       610        620        630        640        650        660 
SMLPRLRPRQ YYDLVVQVAI VRPGPIQGGM VHPYLRRRQG REDITYPGPA VRKALARTLG 

       670        680        690        700        710        720 
VPIFQEQVMQ IAVDAAGFTP GEADALRRSM AAWRRKGGVD KFRAQLVGGL LARNYTADFA 

       730        740        750        760        770        780 
QALFRQIEGF GEYGFPESHA ASFALLAYAS SWLKCHEPEA FLAALLNSQP MGFYAPAQLV 

       790        800        810        820        830        840 
QDARRHGVRV LPADVLYSGW EASLQDAPGA ARPAVRLGLN LVKGLREDSA RAIEQARVRR 

       850        860        870        880        890        900 
PFADTADMAR RAGLPRQALD ALAAADALRT LAGHRRLASW QAAASAQSRD LLREAVIVET 

       910        920        930        940        950        960 
ETPALPAPSE GQTVAADYRS VGLTLGRHPL ALLRPQLAAR NFQTAAVLNT YPNRRLARAC 

       970        980        990       1000       1010       1020 
GIVTVRQRPQ TAKGTIFVTL EDETGPINAV VRPELIERQR RELLDATLLG IYGTWQSVDG 

      1030       1040       1050 
VRHLVAQRLV DLSSLLGQLS QDGLAAASRN FH
Q7WHW8 in FASTA format

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