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UniProtKB/Swiss-Prot entry Q7WF77


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRB_BORBR
Primary accession number Q7WF77
Secondary accession numbers None
Integrated into Swiss-Prot on April 26, 2004
Sequence was last modified on October 1, 2003 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 34)
Name and origin of the protein
Protein name Aspartate carbamoyltransferase
Synonyms EC 2.1.3.2
Aspartate transcarbamylase
ATCase
Gene name
Name: pyrB
OrderedLocusNames: BB4403
From
Bordetella bronchiseptica (Alcaligenes bronchisepticus) [TaxID: 518] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales; Alcaligenaceae; Bordetella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=RB50 / ATCC BAA-588 / NCTC 13252;
DOI=10.1038/ng1227; PubMed=12910271 [NCBI, ExPASy, EBI, Israel, Japan]
Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R., Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L., Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A., Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I., Chillingworth T., Collins M., Cronin A., Davis P., Doggett J., Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K., Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C., Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K., Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K., Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
"Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica.";
Nat. Genet. 35:32-40(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BX640450; CAE34766.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq NP_890937.1; -.
3D structure databases
ModBase Q7WF77.
Enzyme and pathway databases
BioCyc BBRO257310:BB4403-MON; -.
Ontologies
GO
GO:0004070; Molecular function: aspartate carbamoyltransferase activity (inferred from electronic annotation from HAMAP).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00001; -; 1.
PBIL [Tree]
InterPro IPR006130; Asp/Orn_carbamoyltranf.
IPR006132; Asp/Orn_carbamoyltranf_P_bd.
IPR006131; Asp_carbamoyltransf_Asp/Orn_bd.
IPR002082; Aspartate_carbamoyltransf_euk.
Graphical view of domain structure.
Pfam PF00185; OTCace; 1.
PF02729; OTCace_N; 1.
Pfam graphical view of domain structure.
PRINTS PR00100; AOTCASE.
PR00101; ATCASE.
TIGRFAMs TIGR00670; asp_carb_tr; 1.
PROSITE PS00097; CARBAMOYLTRANSFERASE; 1.
BLOCKS Q7WF77.
Genome annotation databases
GeneID 2660325; -.
GenomeReviews BX470250_GR; BB4403.
KEGG bbr:BB4403; -.
Phylogenomic databases
HOGENOM Q7WF77; -.
Genome annotation databases
CMR Q7WF77; BB4403.
Other
ProtoNet Q7WF77.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Pyrimidine biosynthesis; Transferase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   317  317     Aspartate carbamoyltransferase. PRO_0000113104
Sequence information
Length: 317 AA [This is the length of the unprocessed precursor] Molecular weight: 34362 Da [This is the MW of the unprocessed precursor] CRC64: 464A99C633295756 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MLNPQLNRHG ELIHLLSTEG LPRRIIEQIL DLAATFVPAP GQEFPKLPLL HGKSVFNLFF 

        70         80         90        100        110        120 
ENSTRTRTTF EIAAKRLSAD VVNLNIAASS TSKGESLLDT IANLSAMQAD LFVVRHGASG 

       130        140        150        160        170        180 
APYLIAQHVA PHVHVINAGD GRHAHPTQAL LDMYTIRHHK GDFNQLTVAI VGDVLHSRVA 

       190        200        210        220        230        240 
RSDIHALTTL GVPEVRVVAP ATLLPEGLAQ MGVRVCTDME EGLRDADVVI MLRLQNERMR 

       250        260        270        280        290        300 
GALLPSAHEY FKHYGLTQAR LALARPDAIV MHPGPMNRGV EIASEVADSG QAVILDQVTF 

       310 
GIAVRMAAMS LVAGVRP 

Q7WF77 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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